# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4616904 | B | Inhibition of HSET in Schizosaccharomyces pombe TY27 overexpressing GFP-HSET assessed as inhibition of HSET overproduction-induced lethal growth defects by measuring growth restoring activity incubated for 3 days by agar plate-based method | Schizosaccharomyces pombe | 4 | ALA4616587 | assay format | Scientific Literature | |
2. | ALA4616905 | B | Inhibition of HSET in Schizosaccharomyces pombe TY27 overexpressing GFP-HSET assessed as inhibition of HSET overproduction-induced lethal growth defects by measuring growth restoring activity at 25 ng/spot incubated for 3 days by agar plate-based method | Schizosaccharomyces pombe | 1 | ALA4616587 | assay format | Scientific Literature | |
3. | ALA4616908 | B | Inhibition of HSET in Schizosaccharomyces pombe TY27 overexpressing GFP-HSET assessed as inhibition of HSET overproduction-induced lethality by measuring cell growth at 0.25 uM incubated for 2 to 3 days (Rvb = 8%) | Schizosaccharomyces pombe | 1 | ALA4616587 | assay format | Scientific Literature | |
4. | ALA4616911 | B | Inhibition of HSET in Schizosaccharomyces pombe TY27 overexpressing GFP-HSET assessed as inhibition of HSET overproduction-induced lethality by measuring cell viability at 0.25 uM incubated for 2 to 3 days relative to control | Schizosaccharomyces pombe | 1 | ALA4616587 | assay format | Scientific Literature | |
5. | ALA4616913 | B | Inhibition of HSET in Schizosaccharomyces pombe TY27 overexpressing GFP-HSET assessed as reversion of HSET-induced lethal abnormal monopolar spindle formation to bipolar formation by measuring cells containing monopolar spindles at 0.01 ug/ml incubated for 2 days by wide field inverted epifluorescence microscopic method (Rvb = 76%) | Schizosaccharomyces pombe | 1 | ALA4616587 | assay format | Scientific Literature | |
6. | ALA4616914 | B | Inhibition of HSET in Schizosaccharomyces pombe TY27 overexpressing GFP-HSET assessed as reversion of HSET-induced lethal abnormal monopolar spindle formation to bipolar formation by measuring cells containing monopolar spindles at 0.1 ug/ml incubated for 2 days by wide field inverted epifluorescence microscopic method (Rvb = 76%) | Schizosaccharomyces pombe | 3 | ALA4616587 | assay format | Scientific Literature | |
7. | ALA4616916 | B | Inhibition of HSET in human MDA-MB-231 cells overexpressing HSET and possessing supernumerary centrosomes assessed as inhibition of centrosome clustering by measuring bipolar spindle formation at 20 uM incubated for 24 hrs by Hoechst 33342 staining based fluorescence microscopic method relative to control | Homo sapiens | 1 | ALA4616587 | cell-based format | Scientific Literature | |
8. | ALA4616917 | B | Inhibition of HSET in human MDA-MB-231 cells overexpressing HSET and possessing supernumerary centrosomes assessed as inhibition of centrosome clustering by measuring bipolar spindle formation at 40 uM incubated for 24 hrs by Hoechst 33342 staining based fluorescence microscopic method relative to control | Homo sapiens | 1 | ALA4616587 | cell-based format | Scientific Literature | |
9. | ALA4616918 | B | Inhibition of HSET in human MDA-MB-231 cells overexpressing HSET and possessing supernumerary centrosomes assessed as inhibition of centrosome clustering by measuring increase in multipolar spindle formation at 20 uM incubated for 24 hrs by Hoechst 33342 staining based fluorescence microscopic method relative to control | Homo sapiens | 1 | ALA4616587 | cell-based format | Scientific Literature | |
10. | ALA4616919 | B | Inhibition of HSET in human MDA-MB-231 cells overexpressing HSET and possessing supernumerary centrosomes assessed as inhibition of centrosome clustering by measuring increase in multipolar spindle formation at 40 uM incubated for 24 hrs by Hoechst 33342 staining based fluorescence microscopic method relative to control | Homo sapiens | 1 | ALA4616587 | cell-based format | Scientific Literature | |
11. | ALA4616920 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 4 | ALA4616587 | cell-based format | Scientific Literature | |
12. | ALA4616921 | F | Antiproliferative activity against human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 3 | ALA4616587 | cell-based format | Scientific Literature | |
13. | ALA4616923 | B | Inhibition of HSET in human MDA-MB-231 cells overexpressing HSET and possessing supernumerary centrosomes assessed as inhibition of centrosome clustering by measuring increase in multipolar spindle formation incubated for 24 hrs by Hoechst 33342 staining based fluorescence microscopic method | Homo sapiens | 1 | ALA4616587 | cell-based format | Scientific Literature | |
14. | ALA4616927 | B | Inhibition of HSET in Schizosaccharomyces pombe TY27 overexpressing GFP-HSET assessed as inhibition of HSET overproduction-induced lethality by measuring increase in cell viability at 0.25 uM incubated for 2 to 3 days relative to control | Schizosaccharomyces pombe | 1 | ALA4616587 | assay format | Scientific Literature |