# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4629122 | Binding | Binding affinity to HSP90 (unknown origin) by Line weaver-Burk plot analysis | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature | |
2. | ALA4629123 | Functional | Antiproliferative activity against BRCA1-deficient human MX1 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
3. | ALA4629124 | Functional | Antiproliferative activity against BRCA1-deficient human HCC1937 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
4. | ALA4629125 | Functional | Antiproliferative activity against BRCA2-deficient human Capan1 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
5. | ALA4629126 | Functional | Antiproliferative activity against BRCA-proficient human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
6. | ALA4629127 | Functional | Antiproliferative activity against BRCA-proficient human SKBR3 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
7. | ALA4629128 | Functional | Antiproliferative activity against BRCA-proficient human MDA-MB-231 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
8. | ALA4629129 | Functional | Potency index, ratio of compound IC50 to Olaparib IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 2 | ALA4627353 | cell-based format | Scientific Literature | |
9. | ALA4629130 | Binding | Inhibition of PARP in human MCF7 cells assessed as down regulation of PAR at 1 to 100 uM in presence of adriamycin by western blotting analysis | Homo sapiens | 3 | ALA4627353 | cell-based format | Scientific Literature | |
10. | ALA4629131 | Binding | Inhibition of HSP90 in human MDA-MB-231 cells assessed as down regulation of BRCA1 protein expression at 1 to 100 uM in presence of adriamycin by western blotting analysis | Homo sapiens | 1 | ALA4627353 | cell-based format | Scientific Literature | |
11. | ALA4629132 | Binding | Inhibition of HSP90 (unknown origin) by fluorescence quenching method | Homo sapiens | 1 | ALA4627353 | protein format | Scientific Literature | |
12. | ALA4629133 | Binding | Binding affinity to HSP90 (unknown origin) assessed as Stern-Volmer quenching constant by Stern-Volmer plot analysis | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature | |
13. | ALA4629134 | Binding | Binding affinity to HSP90 (unknown origin) assessed as quenching constant by Stern-Volmer plot analysis | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature | |
14. | ALA4629136 | Binding | Binding affinity to HSP90 (unknown origin) by fluorescence quenching method | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature | |
15. | ALA5138218 | Functional | Antiproliferative activity against BRCA proficient human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 2 | ALA5136991 | cell-based format | Scientific Literature | |
16. | ALA5138219 | Functional | Ratio of olaparib IC50 to test compound IC50 for antiproliferative against BRCA proficient human MCF7 cells | Homo sapiens | 1 | ALA5136991 | cell-based format | Scientific Literature | |
17. | ALA5138220 | Functional | Antiproliferative activity against BRCA deficient human HCC1937 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 2 | ALA5136991 | cell-based format | Scientific Literature | |
18. | ALA5138221 | Functional | Ratio of olaparib IC50 to test compound IC50 for antiproliferative against BRCA deficient human HCC1937 cells | Homo sapiens | 1 | ALA5136991 | cell-based format | Scientific Literature | |
19. | ALA5138222 | Functional | Antiproliferative activity against BRCA1 deficient human MX1 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA5136991 | cell-based format | Scientific Literature | |
20. | ALA5138223 | Functional | Antiproliferative activity against BRCA2 deficient human CAPAN-1 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 1 | ALA5136991 | cell-based format | Scientific Literature |