# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4624510 | F | Antitrypanosomal activity against Trypanosoma brucei | Trypanosoma brucei | 17 | ALA4622901 | organism-based format | Scientific Literature | |
2. | ALA4624511 | A | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability | Homo sapiens | 17 | ALA4622901 | cell-based format | Scientific Literature | |
3. | ALA4624512 | T | Selectivity index, ratio of CC50 for human HepG2 cells to EC50 for Trypanosoma brucei | 15 | ALA4622901 | assay format | Scientific Literature | ||
4. | ALA4624514 | B | Inhibition of Trypanosoma brucei rhodesain at 10 uM measured after 1 hr relative to control | Trypanosoma brucei | 17 | ALA4622901 | single protein format | Scientific Literature | |
5. | ALA4731361 | F | Antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in human BE(2)-M17 cells pretreated with compound for 2 hrs followed by viral infection at MOI of 1.2 and measured after 7 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 11 | ALA4725463 | organism-based format | Scientific Literature | |
6. | ALA4731362 | T | Selectivity index, ratio of CC50 for cytotoxicity against mouse Neuro-2a cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse Neuro-2a cells | 10 | ALA4725463 | cell-based format | Scientific Literature | ||
7. | ALA4731363 | F | Antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in mouse Neuro-2a cells pretreated with compound for 2 hrs followed by viral infection at MOI of 3.5 and measured after 7 hrs by immunostaining based confocal microscopic analysis | Venezuelan equine encephalitis virus | 11 | ALA4725463 | organism-based format | Scientific Literature | |
8. | ALA4731372 | T | Selectivity index, ratio of CC50 for cytotoxicity against human BE(2)-M17 cells to EC50 for antiviral activity against Venezuelan equine encephalitis virus TC-83 infected in human BE(2)-M17 cells | 10 | ALA4725463 | cell-based format | Scientific Literature | ||
9. | ALA4731378 | A | Cytotoxicity against human SK-N-BE(2)-M17 cells | Homo sapiens | 11 | ALA4725463 | cell-based format | Scientific Literature | |
10. | ALA4731379 | A | Cytotoxicity against mouse N2a cells | Mus musculus | 10 | ALA4725463 | cell-based format | Scientific Literature |