| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4617317 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4617318 | F | Cytotoxicity against human A549 cells assessed as reduction in cell viability after 24 hrs by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4617319 | F | Cytotoxicity against human H460 cells assessed as effect on cell viability at 1 to 50 uM measured after 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4617320 | F | Cytotoxicity against human H460 cells assessed as effect on cell viability at 1 to 50 uM measured after 24 hrs by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4617321 | F | Cytotoxicity against human U87MG cells assessed as effect on cell viability at 1 to 50 uM measured after 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4617322 | F | Cytotoxicity against human U87MG cells assessed as effect on cell viability at 1 to 50 uM measured after 24 hrs by SRB assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4617329 | F | Antimigratory activity against human U87MG cells assessed as inhibition of cell migration measured after 6 hrs by scratch wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4617330 | F | Antimigratory activity against human H460 cells assessed as inhibition of cell migration measured after 24 hrs by scratch wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4617331 | F | Antimigratory activity against human A549 cells assessed as reduction in cell migration at 25 uM measured after 24 hrs by scratch wound healing assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4617337 | F | Antiinvasive activity against human A549 cells assessed as reduction in cell invasion measured after 24 hrs using Diff-quick staining by light microscopy based Boyden chamber assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4617338 | F | Antiinvasive activity against human H460 cells assessed as reduction in cell invasion measured after 24 hrs using Diff-quick staining by light microscopy based Boyden chamber assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4617339 | F | Antiinvasive activity against human U87MG cells assessed as reduction in cell invasion measured after 24 hrs using Diff-quick staining by light microscopy based Boyden chamber assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4617340 | F | Antiinvasive activity against human U87MG cells assessed as reduction in cell invasion at 25 to 50 uM measured after 24 hrs using Diff-quick staining by light microscopy based Boyden chamber assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4617343 | B | Inhibition of human recombinant ALKBH5 demethylase activity assessed as increase in methylated 6A-RNA level incubated for 30 min by dot blot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4617344 | B | Inhibition of human recombinant ALKBH5 demethylase activity assessed as increase in methylated 6A-RNA level at 10 to 25 uM incubated for 30 min by dot blot analysis relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4617345 | B | Inhibition of ALKBH5 demethylase activity in human U87MG cells assessed as decrease in CD73 expression measured after 1 to 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4617346 | B | Inhibition of ALKBH5 demethylase activity in human U87MG cells assessed as decrease in CD73 expression at 10 uM measured after 2 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4617347 | B | Inhibition of ALKBH5 demethylase activity in human U87MG cells assessed as decrease in CD73 expression at 10 uM measured after 1 hr by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4617348 | F | Effect on CD73 mRNA expression in human U87MG cells at 10 to 25 uM measured after 1 to 6 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5229173 | B | Inhibition of recombinant ALKBH5 (unknown origin) mediated demethylase activity using M6A ssRNA with GG-m6A-CU sequence as substrate assessed as increase in m6A level in RNA at 25 uM incubated for 30 mins relative to control | Homo sapiens | 1 | single protein format | Scientific Literature |
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