# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4628559 | B | Displacement of Cy5-conjugated CELMoD from N-terminal 6-His tagged CRBN (1 to 442 residues) (unknown origin)/DDB1 (1 to 1140 residues) (unknown origin) incubated for 10 mins by FRET assay | Homo sapiens | 12 | protein format | Scientific Literature | ||
2. | ALA4628560 | P | Drug metabolism in assay cell medium assessed as compound racemization measured within 24 hrs | 3 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA4628568 | P | Drug metabolism in aqueous buffer at pH 7.4 assessed as compound racemization measured within 24 hrs | 2 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA4628569 | B | Induction of CRBN-mediated pLOC-ePL-tagged aiolos (unknown origin) degradation in human DF15 cells assessed as minimum protein remaining at 0.00001 to 0.1 uM incubated for 45 to 180 mins by luminescence based beta-galactosidase enzyme fragmentation complementation assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA4628586 | A | Cmax in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
6. | ALA4628588 | A | AUC (0 to infinity) in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
7. | ALA4628590 | A | Cmax in monkey at 3 mg/kg, po | Macaca mulatta | 2 | organism-based format | Scientific Literature | ||
8. | ALA4628591 | A | AUC (0 to infinity) in monkey at 3 mg/kg, po | Macaca mulatta | 2 | organism-based format | Scientific Literature | ||
9. | ALA4628595 | A | Drug metabolism in rat assessed as compound racemization at 10 mg/kg, po relative to compound AUC | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA4628596 | A | Drug metabolism in monkey assessed as compound racemization at 3 mg/kg, po relative to compound AUC | Macaca mulatta | 1 | organism-based format | Scientific Literature |