#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4604220	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as induction of CDK2 protein degradation at 1 uM after 12 hrs by Western blot analysis	Homo sapiens	3	ALA4602651	cell-based format	Scientific Literature
2.	ALA4604224	Binding	Protac activity at CRBN/CDK2 in AR-negative human PC3 cells assessed as induction of CDK2 protein degradation at 50 nM after 12 hrs by Western blot analysis	Homo sapiens	5	ALA4602651	cell-based format	Scientific Literature
3.	ALA4604225	Binding	Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 50 nM after 12 hrs by Western blot analysis	Homo sapiens	5	ALA4602651	cell-based format	Scientific Literature
4.	ALA4604226	Functional	Antiproliferative activity against AR-negative human PC3 cells assessed as reduction in cell viability after 5 days by CCK8 assay	Homo sapiens	22	ALA4602651	cell-based format	Scientific Literature
5.	ALA4604227	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as induction of CDK2 protein degradation after 24 hrs by Western blot analysis	Homo sapiens	4	ALA4602651	cell-based format	Scientific Literature
6.	ALA4604228	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation after 24 hrs by Western blot analysis	Homo sapiens	4	ALA4602651	cell-based format	Scientific Literature
7.	ALA4604229	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 500 nM after 4 hrs by Western blot analysis relative to control	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
8.	ALA4604230	Binding	Protac activity at CRBN/CDK4 in AR-negative human PC3 cells assessed as induction of CDK4 protein degradation at 500 nM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
9.	ALA4604231	Binding	Protac activity at CRBN/CDK6 in AR-negative human PC3 cells assessed as induction of CDK4 protein degradation at 500 nM after 24 hrs by Western blot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
10.	ALA4604232	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as reduction in c-Myc protein expression at 500 nM measured after 2 to 24 hrs by Western blot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
11.	ALA4604233	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as CDK2 degradation at 250 nM preincubated with pomalidomide for 2 hrs and measured after 8 hrs by Western blot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
12.	ALA4604234	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as CDK2 degradation at 250 nM preincubated with FN-1501 for 2 hrs and measured after 8 hrs by Western blot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
13.	ALA4604235	Binding	Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as CDK2 degradation at 250 nM preincubated with proteasome inhibitor MG132 for 2 hrs and measured after 8 hrs by Western blot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
14.	ALA4604241	ADME	Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 5 days by CCK-8 assay	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
15.	ALA4604242	Binding	Inhibition of tracer K10 binding to NanoLuc-CDK2/Cyclin A (unknown origin) expressed in human HEK293 cells after 1 hr in presence of ATP by NanoBRET assay	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
16.	ALA4604243	Binding	Inhibition of tracer K10 binding to NanoLuc-CDK9/Cyclin T1 (unknown origin) expressed in human HEK293 cells after 1 hr in presence of ATP by NanoBRET assay	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
17.	ALA4604244	Binding	Protac activity at CRBN/CDK2/CDK9 in human MCF7 cells assessed as CDK2 degradation at 0.25 to 10 uM after 12 hrs by Westernblot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
18.	ALA4604245	Binding	Protac activity at CRBN/CDK2/CDK9 in human HCT116 cells assessed as CDK2 degradation at 0.25 to 10 uM after 12 hrs by Westernblot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
19.	ALA4604246	Binding	Protac activity at CRBN/CDK2/CDK9 in human 22Rv1 cells assessed as CDK2 degradation at 0.25 to 10 uM after 12 hrs by Westernblot analysis	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature
20.	ALA4604247	Functional	Induction of cell cycle arrest in human PC3 cells assessed as accumulation at G0/G1 phase at 250 nM after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 59.80%)	Homo sapiens	1	ALA4602651	cell-based format	Scientific Literature