# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4617153 | F | Antiviral activity against TBEV | Tick-borne encephalitis virus | 2 | organism-based format | Scientific Literature | ||
2. | ALA4617154 | F | Antiviral activity against Zika virus | Zika virus | 2 | organism-based format | Scientific Literature | ||
3. | ALA4617155 | F | Antiviral activity against Dengue virus | Dengue virus | 2 | organism-based format | Scientific Literature | ||
4. | ALA4617156 | F | Antiviral activity against West Nile virus | West Nile virus | 2 | organism-based format | Scientific Literature | ||
5. | ALA4617157 | F | Antiviral activity against CVB3 | Coxsackievirus | 2 | organism-based format | Scientific Literature | ||
6. | ALA4617158 | F | Antiviral activity against HIV | Human immunodeficiency virus | 2 | organism-based format | Scientific Literature | ||
7. | ALA4617159 | A | Prodrug activation in human HepG2 cell extract assessed as metabolite formation at 100 uM measured after 4 hrs by HPLC analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA4617160 | P | Prodrug activation assessed as formation of diastereoisomers at 12.9 ppm by P-NMR spectroscopy | 1 | small-molecule physicochemical format | Scientific Literature | |||
9. | ALA4617161 | P | Prodrug activation assessed as formation of diastereoisomers at 12.6 ppm by P-NMR spectroscopy | 1 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA4617164 | A | Prodrug activation assessed as carboxypeptidase Y (unknown origin) mediated cleavage of diastereoisomer measured after 5 mins by P-NMR spectroscopy | Homo sapiens | 2 | assay format | Scientific Literature | ||
11. | ALA4617165 | A | Prodrug activation assessed as carboxypeptidase Y (unknown origin) mediated signal shift at 13.5 ppm by P-NMR spectroscopy | Homo sapiens | 1 | assay format | Scientific Literature | ||
12. | ALA4617166 | A | Prodrug activation assessed as carboxypeptidase Y (unknown origin) mediated signal shift at 13.2 ppm by P-NMR spectroscopy | Homo sapiens | 1 | assay format | Scientific Literature | ||
13. | ALA4617167 | A | Prodrug activation assessed as carboxypeptidase Y (unknown origin) mediated metabolite formation at 3.3 ppm by P-NMR spectroscopy | Homo sapiens | 1 | assay format | Scientific Literature | ||
14. | ALA4617168 | A | Prodrug activation assessed as carboxypeptidase Y (unknown origin) mediated (2S)-2-((((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methylamino)(phenoxy)phosphorylamino)propanoic acid intermediate formation measured after 5 mins by P-NMR spectroscopy | Homo sapiens | 1 | assay format | Scientific Literature | ||
15. | ALA4617169 | A | Prodrug activation assessed as carboxypeptidase Y (unknown origin) mediated cleavage of diastereoisomer measured after 120 mins by P-NMR spectroscopy | Homo sapiens | 2 | assay format | Scientific Literature | ||
16. | ALA4617170 | P | Prodrug activation assessed as formation of free phosphate traces by P-NMR spectroscopy | 1 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA4617171 | A | Prodrug activation assessed as carboxypeptidase Y (unknown origin) mediated formation of metabolite from (2S)-2-((((2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methylamino)(phenoxy)phosphorylamino)propanoic acid intermediate at 3.3 ppm by P-NMR spectroscopy | Homo sapiens | 1 | assay format | Scientific Literature |