| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4614784 | Functional | Inhibition of alternative compliment pathway in serum isolated from beagle dog treated at 3 mg/kg, po assessed as reduction in in MAC deposition measured at 6 hrs post dose by ELISA relative to control | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 2. | ALA4614785 | Functional | Inhibition of alternative compliment pathway in serum isolated from beagle dog treated at 3 mg/kg, po assessed as reduction in in MAC deposition measured at 12 hrs post dose by ELISA relative to control | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 3. | ALA4614795 | ADME | Clearance in Wistar Han rat at 1 mg/kg, iv after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 4. | ALA4614796 | ADME | Volume of distribution at steady state in Wistar Han rat at 1 mg/kg, iv after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 5. | ALA4614797 | ADME | Half life in Wistar Han rat at 1 mg/kg, iv after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 6. | ALA4614798 | ADME | Mean residence time in Wistar Han rat at 1 mg/kg, iv after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 7. | ALA4614799 | ADME | AUC/dose in Wistar Han rat at 1 mg/kg, iv after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 8. | ALA4614800 | ADME | AUC/dose in Wistar Han rat at 30 mg/kg, po after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 9. | ALA4614801 | ADME | Oral bioavailability in Wistar Han rat at 30 mg/kg after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 10. | ALA4614802 | ADME | Cmax/dose in Wistar Han rat at 30 mg/kg, po after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 11. | ALA4614803 | ADME | Tmax in Wistar Han rat at 30 mg/kg, po after 0.5 to 24 hrs by HPLC-MS/MS analysis | Rattus norvegicus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 12. | ALA4614804 | ADME | Clearance in beagle dog at 0.1 mg/kg, iv after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 13. | ALA4614805 | ADME | Volume of distribution at steady state in beagle dog at 0.1 mg/kg, iv after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 14. | ALA4614806 | ADME | Half life in beagle dog at 0.1 mg/kg, iv after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 15. | ALA4614807 | ADME | Mean residence time in beagle dog at 0.1 mg/kg, iv after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 16. | ALA4614808 | ADME | AUC/dose in beagle dog at 0.1 mg/kg, iv after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 17. | ALA4614809 | ADME | AUC/dose in beagle dog at 10 mg/kg, po after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 18. | ALA4614810 | ADME | Oral bioavailability in beagle dog at 10 mg/kg after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 19. | ALA4614811 | ADME | Cmax/dose in beagle dog at 10 mg/kg, po after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 20. | ALA4614812 | ADME | Tmax in beagle dog at 10 mg/kg, po after 15 mins to 24 hrs by HPLC-MS/MS analysis | Canis lupus familiaris | 1 | ALA4613250 | organism-based format | Scientific Literature |
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