# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4627631 | F | Induction of DNA damage in human SU8686 cells assessed as increase in gammaH2AX phosphorylation at ser193 at cytotoxic IC50 incubated for 24 hrs by fluorometry method | Homo sapiens | 17 | ALA4627257 | cell-based format | Scientific Literature | |
2. | ALA4627632 | F | Cytotoxicity against human BxPC3 cells assessed as cell viability after 72 hrs incubated with resazurin sodium salt by Alamar blue assay | Homo sapiens | 2 | ALA4627257 | cell-based format | Scientific Literature | |
3. | ALA4627633 | F | Cytotoxicity against human SU8686 cells assessed as cell viability after 72 hrs incubated with resazurin sodium salt by Alamar blue assay | Homo sapiens | 2 | ALA4627257 | cell-based format | Scientific Literature | |
4. | ALA4627634 | F | Induction of DNA damage in human SU8686 cells assessed as increase in gammaH2AX phosphorylation at ser193 at cytotoxic IC50 in presence of 5 uM cisplatin by fluorometry method | Homo sapiens | 17 | ALA4627257 | cell-based format | Scientific Literature | |
5. | ALA4627635 | F | Induction of DNA damage in human SU8686 cells assessed as increase in gammaH2AX phosphorylation at ser193 at cytotoxic IC50 in presence of 0.3 uM doxorubicin by fluorometry method | Homo sapiens | 39 | ALA4627257 | cell-based format | Scientific Literature | |
6. | ALA4627638 | F | Induction of DNA damage in human SU8686 cells assessed as tail DNA formation at IC50 by alkaline Comet assay | Homo sapiens | 10 | ALA4627257 | cell-based format | Scientific Literature | |
7. | ALA4627639 | F | Induction of DNA damage in human SU8686 cells assessed as increase gammaH2AX protein level at IC50 for 24 hrs in presence of 5 uM cisplatin by western blot analysis | Homo sapiens | 7 | ALA4627257 | cell-based format | Scientific Literature | |
8. | ALA4627641 | F | Induction of DNA damage in human SU8686 cells assessed as increase in gammaH2AX nuclear foci under basal condition at IC50 by fluorometry method | Homo sapiens | 8 | ALA4627257 | cell-based format | Scientific Literature |