| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4622714 | A | Agonist activity at human TRPC4/TRPC1 expressed in HEK293 Tet cells assessed as increase in intracellular calcium level at 1 uM measured at 5 secs interval for 300 secs by Fura-2AM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA4622715 | A | Agonist activity at human TRPC4/TRPC1 expressed in HEK293 Tet cells assessed as increase in intracellular calcium level at 0.1 uM measured at 5 secs interval for 300 secs by Fura-2AM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA4622716 | A | Agonist activity at human TRPC4/TRPC1 expressed in HEK293 Tet cells assessed as increase in intracellular calcium level at 1 uM measured at 5 secs interval for 300 secs in presence of TRPC4/5 antagonist Pico145 by Fura-2AM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA4622717 | T | Acute toxicity in iv dosed mouse assessed as maximum tolerated dose by up and down method | Mus musculus | 5 | organism-based format | Scientific Literature | ||
| 5. | ALA4622718 | A | Agonist activity at human TRPC5 expressed in HEK293 Tet cells assessed as increase in intracellular calcium level at 10 nM measured at 5 secs interval for 300 secs by Fura-2AM dye based fluorescence assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA4622719 | F | Growth inhibition of human A498 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4622720 | F | Growth inhibition of human UO31 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA4622721 | F | Growth inhibition of human RXF393 cells | Homo sapiens | 4 | cell-based format | Scientific Literature |
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