| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4614541 | Functional | Induction of cell proliferation in human Gingival fibroblast at 1 uM after 72 hrs by MTS assay | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 2. | ALA4614544 | Functional | Protective activity against H202-induced cell death in human Gingival fibroblast assessed as cell proliferation after 72 hrs by MTS assay (Rvb = 50.9 +/- 4%) | Homo sapiens | 2 | ALA4613247 | cell-based format | Scientific Literature | |
| 3. | ALA4614545 | Functional | Antioxidant activity in human Gingival fibroblast assessed as reduction in intracellular ROS level at 1 uM after 72 hrs by H2DCFDA staining based fluorescence method | Homo sapiens | 2 | ALA4613247 | cell-based format | Scientific Literature | |
| 4. | ALA4614546 | Functional | Antioxidant activity in human Gingival fibroblast assessed as reduction in H202-induced intracellular ROS level by measuring ROS production at 1 to 5 uM after 72 hrs by H2DCFDA staining based fluorescence method (Rvb = 181.9 +/- 7.4%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 5. | ALA4614548 | ADME | Induction of cell death in human Gingival fibroblast assessed as live cell at 1 uM after 72 hrs by flow cytometry (Rvb = 97%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 6. | ALA4614549 | ADME | Induction of cell death in human Gingival fibroblast assessed as dead cell at 1 uM after 72 hrs by flow cytometry (Rvb = 3%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 7. | ALA4614550 | Functional | Protection against H202-induced cell death in human Gingival fibroblast assessed as live cell at 1 to 5 uM after 72 hrs by flow cytometry (Rvb = 85.1%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 8. | ALA4614551 | Functional | Protection against H202-induced cell death in human Gingival fibroblast assessed as dead cell at 1 to 5 uM after 72 hrs by flow cytometry (Rvb = 14.9%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 9. | ALA4614552 | ADME | Induction of cell cycle arrest in human Gingival fibroblast assessed as accumulation at G0/G1 phase at 1 uM incubated for 72 hrs by flow cytometry (Rvb = 76.3%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 10. | ALA4614553 | ADME | Induction of cell cycle arrest in human Gingival fibroblast assessed as accumulation at S phase at 1 uM incubated for 72 hrs by flow cytometry (Rvb = 5%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 11. | ALA4614554 | ADME | Induction of cell cycle arrest in human Gingival fibroblast assessed as accumulation at G2/M phase at 1 uM incubated for 72 hrs by flow cytometry (Rvb = 14.9%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 12. | ALA4614555 | Functional | Protection against H202-induced cell cycle blockade in human Gingival fibroblast assessed as accumulation at G0/G1 phase at 1 to 5 uM after 72 hrs by flow cytometry (Rvb = 42.2%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 13. | ALA4614556 | Functional | Protection against H202-induced cell cycle blockade in human Gingival fibroblast assessed as accumulation at S phase at 1 to 5 uM after 72 hrs by flow cytometry (Rvb = 11.6%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 14. | ALA4614557 | Functional | Protection against H202-induced cell cycle blockade in human Gingival fibroblast assessed as accumulation at G2/M phase at 1 to 5 uM after 72 hrs by flow cytometry (Rvb = 39.3%) | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 15. | ALA4614558 | ADME | Effect on p53 mRNA expression in human Gingival fibroblast at 1 uM after 72 hrs by RT-PCR method | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 16. | ALA4614559 | ADME | Effect on p21 mRNA expression in human Gingival fibroblast at 1 uM after 72 hrs by RT-PCR method | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 17. | ALA4614560 | ADME | Effect on p16Ink4a mRNA expression in human Gingival fibroblast at 1 uM after 72 hrs by RT-PCR method | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 18. | ALA4614561 | Functional | Protection against H202-induced oxidative stress in human Gingival fibroblast assessed as reduction in p53 expression at 1 to 5 uM after 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 19. | ALA4614562 | Functional | Protection against H202-induced oxidative stress in human Gingival fibroblast assessed as reduction in p21 expression at 1 to 5 uM after 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature | |
| 20. | ALA4614563 | Functional | Protection against H202-induced oxidative stress in human Gingival fibroblast assessed as reduction in p16Ink4a expression at 1 to 5 uM after 72 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4613247 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!