#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4620705	B	Binding affinity to human RORgamma LBD by thermofluor thermal shift assay	Homo sapiens	68		single protein format	Scientific Literature
2.	ALA4620706	B	Inverse agonist activity at human RORgammat LBD by M1H cell based assay	Homo sapiens	69		cell-based format	Scientific Literature
3.	ALA4620707	B	Inverse agonist activity at RORgammat in human whole blood assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies-stimulated IL-17A production measured after 3 days by ELISA	Homo sapiens	48		tissue-based format	Scientific Literature
4.	ALA4620708	B	Binding affinity to human RORbeta by thermofluor assay	Homo sapiens	68		single protein format	Scientific Literature
5.	ALA4620709	B	Inverse agonist activity at human RORgammat LBD by M1H cell based assay relative to T0901317	Homo sapiens	69		cell-based format	Scientific Literature
6.	ALA4620710	B	Inverse agonist activity at RORgammat in human whole blood assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies-stimulated IL-17A production at 1 uM measured after 3 days by ELISA relative to JNJ-54271074	Homo sapiens	48		tissue-based format	Scientific Literature
7.	ALA4620711	P	Solubility of the compound at pH 7		53		small-molecule physicochemical format	Scientific Literature
8.	ALA4620712	P	Solubility of the compound at pH 2		51		small-molecule physicochemical format	Scientific Literature
9.	ALA4620713	B	Activation of PXR (unknown origin) at 1 uM relative to control	Homo sapiens	62		single protein format	Scientific Literature
10.	ALA4620714	B	Activation of PXR (unknown origin) at 5 uM relative to control	Homo sapiens	56		single protein format	Scientific Literature
11.	ALA4620715	B	Activation of PXR (unknown origin) at 10 uM relative to control	Homo sapiens	10		single protein format	Scientific Literature
12.	ALA4620716	F	In vivo inhibition of RORgammat in mouse assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies/IL-23-stimulated IL-17A production in blood at 30 mg/kg, po followed by ex vivo stimulation of anti-CD3/anti-CD28 monoclonal antibodies/IL-23 measured after 1 hr of compound administration by ELISA relative to control	Mus musculus	1		organism-based format	Scientific Literature
13.	ALA4620717	F	In vivo inhibition of RORgammat in mouse assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies/IL-23-stimulated IL-17A production in blood at 3 mg/kg, po followed by ex vivo stimulation of anti-CD3/anti-CD28 monoclonal antibodies/IL-23 measured after 1 hr of compound administration by ELISA relative to control	Mus musculus	1		organism-based format	Scientific Literature
14.	ALA4620718	F	In vivo inhibition of RORgammat in mouse assessed as inhibition of anti-CD3/anti-CD28 monoclonal antibodies/IL-23-stimulated IL-17A production in blood at 30 mg/kg, po followed by ex vivo stimulation of anti-CD3/anti-CD28 monoclonal antibodies/IL-23 measured after 4 hrs of compound administration by ELISA relative to control	Mus musculus	1		organism-based format	Scientific Literature
15.	ALA4620719	A	Half life in rat liver microsomes	Rattus norvegicus	13		microsome format	Scientific Literature
16.	ALA4620720	A	Half life in human liver microsomes	Homo sapiens	13		microsome format	Scientific Literature
17.	ALA4620721	A	Inhibition of CYP1A2 (unknown origin)	Homo sapiens	11		single protein format	Scientific Literature
18.	ALA4620722	A	Inhibition of CYP2C19 (unknown origin)	Homo sapiens	12		single protein format	Scientific Literature
19.	ALA4620723	A	Inhibition of CYP2C8 (unknown origin)	Homo sapiens	11		single protein format	Scientific Literature
20.	ALA4620724	A	Inhibition of CYP2C9 (unknown origin)	Homo sapiens	12		single protein format	Scientific Literature