| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4617887 | F | Inhibition of LPS-induced iNOS protein expression in mouse RAW264.7 cells at 0.5 to 4 uM preincubated for 1 hr followed by LPS-stimulation and measured after 16 hrs by immunoblot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4617888 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in quinone reductase activity incubated for 24 hrs by MTT based assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4617889 | B | Activation of Nrf2 in mouse Hepa1c1c7 cells assessed as increase in quinone reductase activity at 3.12 uM incubated for 24 hrs by MTT based assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4617891 | B | Activation of Nrf2 in human MDA-MB-231 cells assessed as increase in ARE luciferase activity at 0.13 to 2 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4617892 | B | Activation of Nrf2 in human MDA-MB-231 cells assessed as increase in ARE luciferase activity at 2 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4617893 | B | Activation of Nrf2 in human MDA-MB-231 cells assessed as increase in ARE luciferase activity at > 4 uM incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4617894 | A | Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability at 0.13 to 10 uM after 24 to 48 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4617895 | B | Activation of Nrf2 in human MDA-MB-231 cells assessed as increase in luciferase activity incubated for 16 hrs by dual luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4617896 | B | Activation of Nrf2 in human MDA-MB-231 cells assessed as increase in Nrf2 protein level at 0.5 uM incubated for 16 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4617897 | B | Activation of Nrf2 in human MDA-MB-231 cells assessed as increase in NQO1 protein level at 0.5 uM incubated for 16 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4617898 | B | Activation of Nrf2 in human MDA-MB-231 cells assessed as increase in GCLM protein level at 0.5 uM incubated for 16 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4617902 | A | Cytotoxicity against human BEAS2B cells assessed as decrease in cell viability at < 12.5 uM after 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4617903 | B | Activation of Nrf2 in human BEAS2B cells assessed as increase in Nrf2 protein level incubated for 12 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4617904 | B | Activation of Nrf2 in human BEAS2B cells assessed as increase in NQO1 protein expression incubated for 12 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4617905 | B | Activation of Nrf2 in human BEAS2B cells assessed as increase in GCLM protein expression incubated for 12 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4617906 | B | Activation of Nrf2 in human BEAS2B cells assessed as increase in KEAP1 protein expression at 0.25 to 2 uM incubated for 12 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4617907 | B | Activation of Nrf2 in human BEAS2B cells at 0.25 to 2 uM incubated for 12 hrs by immunoblot analysis relative to SF | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4617908 | B | Activation of Nrf2 in human BEAS2B cells assessed as increase in Nrf2 protein expression at 1 uM incubated for 8 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4617909 | B | Activation of Nrf2 in human BEAS2B cells assessed as increase in Nrf2 protein expression at 1 uM incubated for 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4617910 | B | Activation of Nrf2 in human BEAS2B cells assessed as increase in luciferase activity at 0.25 to 2 uM incubated for 18 hrs by dual luciferase reporter gene assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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