# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4614752 | Binding | Inhibition of human serine protease factor B by TR-FRET based competition binding assay | Homo sapiens | 16 | ALA4613250 | single protein format | Scientific Literature | |
2. | ALA4614753 | Binding | Inhibition of serine protease factor B in 50% human whole blood assessed as reduction in alternative pathway-mediated membrane attack complex formation pre-incubated for 15 mins before activated zymosan A stimulation for 50 mins by ELISA | Homo sapiens | 7 | ALA4613250 | tissue-based format | Scientific Literature | |
3. | ALA4614754 | Binding | Inhibition of serine protease factor B in 50% mouse serum assessed as reduction in C3b deposition pre-incubated for 15 mins before activated zymosan A stimulation for 50 mins by ELISA | Mus musculus | 7 | ALA4613250 | cell-free format | Scientific Literature | |
4. | ALA4614769 | Functional | Inhibition of C3d+iC3b formation in plasma of C57BL/6 mouse model of LPS-induced AP complement activation at 30 mg/kg, po after 8 hrs | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature | |
5. | ALA4614770 | Functional | Inhibition of C3d+iC3b formation in ocular tissues of C57BL/6 mouse model of LPS-induced AP complement activation at 30 mg/kg, po after 8 hrs | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature |