| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4627766 | B | Agonist activity at TLR8 in human PBMC assessed as induction of myeloid dendritic cell maturation by measuring HLA-DR level at 0.1 uM after 6 hrs by flow cytometry | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA4627768 | B | Agonist activity at TLR8 in human PBMC assessed as induction of myeloid dendritic cell maturation by measuring CD86 level at 0.1 uM after 6 hrs by flow cytometry | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 3. | ALA4627770 | B | Agonist activity at human TLR7 expressed in HEK293 cells assessed as induction of NFKappaB activity after 24 hrs by SEAP reporter gene assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 4. | ALA4627771 | B | Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NFKappaB activity after 24 hrs by SEAP reporter gene assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 5. | ALA4627775 | B | Agonist activity at TLR7/TLR8 in human PBMC assessed as IFN alpha level | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 6. | ALA4627776 | B | Agonist activity at TLR7 in human PBMC assessed as IFNalpha stimulation at 10 uM | Homo sapiens | 13 | cell-based format | Scientific Literature |
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