# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4627975 | A | Half life in human hepatocytes | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
2. | ALA4627976 | B | Inhibition of NS5B polymerase in HCV genotype 1a H77 infected in human HuH7 replicon cells assessed as inhibition of viral replication after 3 days by luciferase reporter gene assay | Hepatitis C virus subtype 1a | 15 | cell-based format | Scientific Literature | ||
3. | ALA4627977 | B | Inhibition of NS5B polymerase in HCV genotype 1b Con1 infected in human HuH7 replicon cells assessed as inhibition of viral replication after 3 days by luciferase reporter gene assay | Hepatitis C virus subtype 1b | 15 | cell-based format | Scientific Literature | ||
4. | ALA4627978 | P | Aqueous solubility of compound at pH 7.4 | 15 | small-molecule physicochemical format | Scientific Literature | |||
5. | ALA4627979 | A | Intrinsic clearance in human hepatocytes | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
6. | ALA4627980 | A | Prodrug conversion in human hepatocytes assessed as nucleotide triphosphate level at 100 uM after 4 hrs | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
7. | ALA4627981 | A | Prodrug conversion in human hepatocytes assessed as nucleotide triphosphate level at 100 uM incubated for 4 hrs followed by compound washout and further incubated in fresh media for 24 hrs | Homo sapiens | 15 | cell-based format | Scientific Literature |