| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4614748 | Binding | Inhibition of human ERG by radioligand binding assay | Homo sapiens | 3 | ALA4613250 | single protein format | Scientific Literature | |
| 2. | ALA4614749 | Binding | Inhibition of adrenergic receptor alpha1a (unknown origin) | Homo sapiens | 3 | ALA4613250 | single protein format | Scientific Literature | |
| 3. | ALA4614750 | Binding | Inhibition of adrenergic receptor alpha2c (unknown origin) | Homo sapiens | 3 | ALA4613250 | single protein format | Scientific Literature | |
| 4. | ALA4614752 | Binding | Inhibition of human serine protease factor B by TR-FRET based competition binding assay | Homo sapiens | 16 | ALA4613250 | single protein format | Scientific Literature | |
| 5. | ALA4614753 | Binding | Inhibition of serine protease factor B in 50% human whole blood assessed as reduction in alternative pathway-mediated membrane attack complex formation pre-incubated for 15 mins before activated zymosan A stimulation for 50 mins by ELISA | Homo sapiens | 7 | ALA4613250 | tissue-based format | Scientific Literature | |
| 6. | ALA4614754 | Binding | Inhibition of serine protease factor B in 50% mouse serum assessed as reduction in C3b deposition pre-incubated for 15 mins before activated zymosan A stimulation for 50 mins by ELISA | Mus musculus | 7 | ALA4613250 | cell-free format | Scientific Literature | |
| 7. | ALA4614755 | Physicochemical | Equilibrium high throughput solubility in aqueous buffer at pH 6.8 | 1 | ALA4613250 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA4614756 | ADME | Intrinsic clearance in mouse liver microsomes | Mus musculus | 1 | ALA4613250 | microsome format | Scientific Literature | |
| 9. | ALA4614757 | ADME | Intrinsic clearance in human liver microsomes | Homo sapiens | 1 | ALA4613250 | microsome format | Scientific Literature | |
| 10. | ALA4614758 | ADME | Apparent permeability across apical to basolateral side in human Caco2 cells | Homo sapiens | 1 | ALA4613250 | cell-based format | Scientific Literature | |
| 11. | ALA4614759 | ADME | Apparent permeability across basolateral to apical side in human Caco2 cells | Homo sapiens | 1 | ALA4613250 | cell-based format | Scientific Literature | |
| 12. | ALA4614760 | ADME | Clearance in C57BL/6 mouse at 1 mg/kg, iv after 5 mins to 7 hrs by HPLC-MS/MS analysis | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature | |
| 13. | ALA4614761 | ADME | Volume of distribution at steady state in C57BL/6 mouse at 1 mg/kg, iv after 5 mins to 7 hrs by HPLC-MS/MS analysis | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature | |
| 14. | ALA4614762 | ADME | Half life in C57BL/6 mouse at 1 mg/kg, iv after 5 mins to 7 hrs by HPLC-MS/MS analysis | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature | |
| 15. | ALA4614763 | ADME | Mean residence time in C57BL/6 mouse at 1 mg/kg, iv after 5 mins to 7 hrs by HPLC-MS/MS analysis | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature | |
| 16. | ALA4614764 | ADME | AUC (0 to last) in C57BL/6 mouse at 10 mg/kg, po after 7 hrs by HPLC-MS/MS analysis | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature | |
| 17. | ALA4614765 | ADME | Cmax in C57BL/6 mouse at 10 mg/kg, po after 5 mins to 7 hrs by HPLC-MS/MS analysis | Mus musculus | 1 | ALA4613250 | organism-based format | Scientific Literature | |
| 18. | ALA4614766 | ADME | Oral bioavailability in C57BL/6 mouse at 10 mg/kg after 5 mins to 7 hrs by HPLC-MS/MS analysis | Mus musculus | 6 | ALA4613250 | organism-based format | Scientific Literature |
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