# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4623530 | B | Inhibition of calf thymus Top1 assessed as reduction in supercoiled pBR322 DNA relaxation at 100 uM measured after 30 mins by agarose gel electrophoresis relative to camptothecin | Bos taurus | 27 | single protein format | Scientific Literature | ||
2. | ALA4623531 | B | Inhibition of TDP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using 5'-FAM-AGGATCTAAAAGACTT-BHQ-3' as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
3. | ALA4623532 | F | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
4. | ALA4623533 | F | Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
5. | ALA4623534 | F | Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTT assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
6. | ALA4623537 | B | Inhibition of TDP1 (unknown origin) expressed in Escherichia coli BL21 (DE3) at 100 uM using 5'-FAM-AGGATCTAAAAGACTT-BHQ-3' as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay relative to control | Homo sapiens | 26 | assay format | Scientific Literature |