# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4620853 | F | Antimelanogenic activity against zebrafish embryo assessed as whitening efficacy at 10 uM | Danio rerio | 20 | ALA4619757 | organism-based format | Scientific Literature | |
2. | ALA4620854 | F | Antimelanogenic activity against zebrafish embryo assessed as whitening efficacy | Danio rerio | 3 | ALA4619757 | organism-based format | Scientific Literature | |
3. | ALA4620855 | F | Antimelanogenic activity against human HMVII cells assessed as change in melanin colour from black to brown | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
4. | ALA4620857 | F | Antimelanogenic activity against human HMVII cells assessed as melanin content in cell lysate at 1 uM relative to control | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
5. | ALA4620858 | F | Antimelanogenic activity against human HMVII cells assessed as melanin content in cell lysate at 10 uM relative to control | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
6. | ALA4620859 | F | Antimelanogenic activity against human HMVII cells assessed as melanin content in cell lysate at 20 uM relative to control | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
7. | ALA4620860 | F | Antimelanogenic activity against human HMVII cells assessed as reduction in TRP1 mRNA level at 1 to 20 uM measured after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
8. | ALA4620861 | F | Antimelanogenic activity against human HMVII cells assessed as reduction in melanin content in cell lysate | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
9. | ALA4620862 | F | Antimelanogenic activity against human HMVII cells assessed as reduction in TRP2 mRNA level at 1 to 20 uM measured after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
10. | ALA4620863 | F | Antimelanogenic activity against human HMVII cells assessed as reduction in MITF mRNA level at 1 to 20 uM measured after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
11. | ALA4620864 | F | Antimelanogenic activity against human HMVII cells assessed as reduction in tyrosinase mRNA level at 10 to 20 uM measured after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
12. | ALA4620865 | A | Cytotoxicity against human HMVII cells assessed as decrease in cell survival at 20 uM measured after 5 days by Cytox-reagent based relative to control | Homo sapiens | 1 | ALA4619757 | cell-based format | Scientific Literature | |
13. | ALA4620866 | T | Toxicity against human eye assessed as effect on tissue viability up to 50 uM measured after 30 mins by MTT assay | Homo sapiens | 1 | ALA4619757 | tissue-based format | Scientific Literature | |
14. | ALA4620867 | T | Toxicity against human skin assessed as effect on tissue viability up to 50 uM measured after 30 mins by MTT assay | Homo sapiens | 1 | ALA4619757 | tissue-based format | Scientific Literature |