# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4624654 | F | Cytotoxicity against human patient derived GBM cells assessed as reduction in cell viability measured after 48 hrs by Hoechst staining based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA4624655 | F | Synergistic cytotoxicity against human patient derived GBM cells assessed as reduction in cell viability measured after 48 hrs in presence of temozolomide by Hoechst staining based assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA4624656 | A | Substrate activity at OATP in human patient derived GBM cells assessed as protein-mediated drug uptake at 1 uM preincubated with 3,4-DHB for 1 hr followed by compound treatment measured after 1 hr by Hoechst staining based fluorescence microscopy | Homo sapiens | 1 | assay format | Scientific Literature | ||
4. | ALA4624657 | A | Substrate activity at OATP in human patient derived GBM cells assessed as protein-mediated drug uptake at 1 uM preincubated with sodium tauro-cholic acid for 30 mins followed by compound treatment measured after 1 hr by Hoechst staining based fluorescence microscopy | Homo sapiens | 1 | assay format | Scientific Literature | ||
5. | ALA4624658 | F | Ratio of EC50 for cytotoxicity against human patient derived GBM assessed as reduction in cell viability measured after 48 hrs by Hoechst staining based assay to EC50 for synergistic cytotoxicity against human patient derived GBM assessed as reduction in cell viability measured after 48 hrs in presence of temozolomide by Hoechst staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4624659 | F | Antiproliferative activity against human patient derived GBM cells assessed as reduction in cell proliferation measured after 48 hrs by Edu incorporation assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
7. | ALA4624660 | F | Synergistic antiproliferative activity against human patient derived GBM cells assessed as reduction in cell proliferation measured after 48 hrs in presence of temozolomide by Edu incorporation assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
8. | ALA4624662 | F | Potency index, ratio of rucaparib IC50 to test compound IC50 for human patient derived GBM cells assessed as reduction in cell viability measured after 48 hrs by Hoechst staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA4624663 | F | Potency index, ratio of IR-786 IC50 to test compound IC50 for human patient derived GBM cells assessed as reduction in cell viability measured after 48 hrs by Hoechst staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA4624664 | F | Potency index, ratio of IR-786 IC50 to test compound IC50 for synergistic cytotoxicity against human patient derived GBM cells assessed as reduction in cell viability measured after 48 hrs in presence of temozolomide by Hoechst staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA4624665 | F | Antiproliferative activity against human patient derived GBM cells assessed as reduction in cell proliferation measured after 48 hrs by Edu incorporation assay relative to compound alone | Homo sapiens | 2 | cell-based format | Scientific Literature |