#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4628266	B	Inhibition of human recombinant C-terminal FLAG-tagged SMS2 expressed in Freestyle293 cell membrane using C14-phosphatidylcholineD72 and C17-ceramide pre-incubated for 60 mins followed by incubation with substrate for 30 mins measured by RapidFire/MS assay	Homo sapiens	17		cell-based format	Scientific Literature
2.	ALA4628267	B	Inhibition of mouse recombinant C-terminal FLAG-tagged SMS2 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramide pre-incubated for 60 mins followed by incubation with substrate for 30 mins measured by RapidFire/MS assay	Mus musculus	17		assay format	Scientific Literature
3.	ALA4628268	A	Inhibition of human recombinant C-terminal FLAG-tagged SMS1 expressed in mammalian expression system using C14-phosphatidylcholineD72 and C17-ceramide pre-incubated for 60 mins followed by incubation with substrate for 30 mins measured by RapidFire/MS assay	Homo sapiens	17		assay format	Scientific Literature
4.	ALA4628269	A	Permeability of compound in buffer solution at pH 7.4 by PAMPA method		8		assay format	Scientific Literature
5.	ALA4628270	P	Aqueous solubility of DMSO dissolved compound in buffer solution at pH 6.8 by LC-MS/MS analysis		8		small-molecule physicochemical format	Scientific Literature
6.	ALA4628271	A	Cmax in KK-AY/Ta mouse at 100 mg/kg, po	Mus musculus	1		organism-based format	Scientific Literature
7.	ALA4628272	A	Drug concentration in KK-AY/Ta mouse at 100 mg/kg, sc measured upto 24 hrs	Mus musculus	1		organism-based format	Scientific Literature
8.	ALA4628273	A	Cmax in KK-AY/Ta mouse at 100 mg/kg, sc	Mus musculus	1		organism-based format	Scientific Literature
9.	ALA4628274	A	Drug concentration in KK-AY/Ta mouse at 100 mg/kg, po measured upto 24 hrs	Mus musculus	1		organism-based format	Scientific Literature
10.	ALA4628275	A	Tmax in KK-AY/Ta mouse at 100 mg/kg, po	Mus musculus	1		organism-based format	Scientific Literature
11.	ALA4628276	A	Tmax in KK-AY/Ta mouse at 100 mg/kg, sc	Mus musculus	1		organism-based format	Scientific Literature
12.	ALA4628277	A	AUC (0 to 24 hrs) in KK-AY/Ta mouse at 100 mg/kg, po	Mus musculus	1		organism-based format	Scientific Literature
13.	ALA4628278	A	AUC (0 to 24 hrs) in KK-AY/Ta mouse at 100 mg/kg, sc	Mus musculus	1		organism-based format	Scientific Literature
14.	ALA4628279	A	MRT in KK-AY/Ta mouse at 100 mg/kg, po	Mus musculus	1		organism-based format	Scientific Literature
15.	ALA4628280	A	MRT in KK-AY/Ta mouse at 100 mg/kg, sc	Mus musculus	1		organism-based format	Scientific Literature
16.	ALA4628281	F	In vivo inhibition of SMS2 in KK-AY/Ta mouse assessed as decrease in hepatic SM (22:00) levels at 100 mg/kg, sc qd for 7 days measured after last dosing by LC/MS analysis	Mus musculus	1		organism-based format	Scientific Literature
17.	ALA4628282	F	In vivo inhibition of SMS2 in KK-AY/Ta mouse assessed as decrease in hepatic SM (22:00) levels at 200 mg/kg, sc bid for 7 days measured after last dosing by LC/MS analysis	Mus musculus	1		organism-based format	Scientific Literature
18.	ALA4628283	F	In vivo inhibition of SMS2 in KK-AY/Ta mouse assessed as decrease in hepatic SM (22:00) levels at 100 mg/kg, po qd for 7 days measured after last dosing by LC/MS analysis	Mus musculus	1		organism-based format	Scientific Literature
19.	ALA4628284	F	In vivo inhibition of SMS2 in KK-AY/Ta mouse assessed as decrease in hepatic SM (22:00) levels at 200 mg/kg, po bid for 7 days measured after last dosing by LC/MS analysis	Mus musculus	1		organism-based format	Scientific Literature