# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4611051 | B | Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 hrs by ELISA | Mus musculus | 14 | cell-based format | Scientific Literature | ||
2. | ALA4611052 | B | Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 18 hrs by ELISA relative to 1V209 | Mus musculus | 14 | cell-based format | Scientific Literature | ||
3. | ALA4611053 | B | Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by ELISA | Mus musculus | 14 | cell-based format | Scientific Literature | ||
4. | ALA4611054 | B | Agonist activity at TLR7 in mouse BMDC cells assessed as immunostimulatory activity by measuring increase in IL6 secretion incubated for 18 hrs by ELISA relative to 1V209 | Mus musculus | 14 | cell-based format | Scientific Literature | ||
5. | ALA4611055 | B | Agonist activity at TLR7 in human PBMC cells assessed as immunostimulatory activity by measuring fold increase in TNFalpha secretion at 10 uM incubated for 18 hrs by ELISA relative to 1V209 | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA4611056 | B | Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion incubated for 6 hrs in absence of actin polymerization inhibitor cytochalasin D by ELISA | Mus musculus | 4 | cell-based format | Scientific Literature | ||
7. | ALA4611057 | B | Agonist activity at TLR7 in mouse RAW264.7 cells assessed as immunostimulatory activity by measuring increase in TNFalpha secretion preincubated with actin polymerization inhibitor cytochalasin D followed by incubation with compound for 6 hrs by ELISA | Mus musculus | 4 | cell-based format | Scientific Literature |