| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4628553 | A | Cytotoxicity against PBMC (unknown origin) | Not specified | 10 | cell-based format | Scientific Literature | ||
| 2. | ALA4628554 | F | Antiproliferative activity against lenalidomide-resistant human H929-R10-1 cells incubated for 5 days by CellTiter-Glo assay | Homo sapiens | 39 | assay format | Scientific Literature | ||
| 3. | ALA4628555 | B | Induction of CRBN-mediated pLOC-ePL-tagged aiolos (unknown origin) degradation in human DF15 cells assessed as minimum protein remaining incubated for 4 hrs by luminescence based beta-galactosidase enzyme fragmentation complementation assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 4. | ALA4628556 | B | Induction of CRBN-mediated pLOC-ePL-tagged aiolos (unknown origin) degradation in human DF15 cells assessed as minimum protein remaining up to 10 uM incubated for 4 hrs by luminescence based beta-galactosidase enzyme fragmentation complementation assay relative to control | Homo sapiens | 39 | cell-based format | Scientific Literature | ||
| 5. | ALA4628557 | B | Induction of CRBN-mediated pLOC-ePL-tagged GSPT1 (unknown origin) degradation in human DF15 cells assessed as minimum protein remaining incubated for 4 hrs by luminescence based beta-galactosidase enzyme fragmentation complementation assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 6. | ALA4628558 | B | Induction of CRBN-mediated pLOC-ePL-tagged GSPT1 (unknown origin) degradation in human DF15 cells assessed as minimum protein remaining up to 10 uM incubated for 4 hrs by luminescence based beta-galactosidase enzyme fragmentation complementation assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4628559 | B | Displacement of Cy5-conjugated CELMoD from N-terminal 6-His tagged CRBN (1 to 442 residues) (unknown origin)/DDB1 (1 to 1140 residues) (unknown origin) incubated for 10 mins by FRET assay | Homo sapiens | 12 | protein format | Scientific Literature | ||
| 8. | ALA4628561 | B | Inhibition of adrenergic receptor alpha1 (unknown origin) at 10 uM relative to control | Homo sapiens | 18 | protein format | Scientific Literature | ||
| 9. | ALA4628562 | B | Inhibition of D2S (unknown origin) at 10 uM relative to control | Homo sapiens | 18 | single protein format | Scientific Literature | ||
| 10. | ALA4628563 | B | Inhibition of adrenergic receptor alpha1 (unknown origin) | Homo sapiens | 2 | protein format | Scientific Literature | ||
| 11. | ALA4628564 | B | Agonist activity at D2S (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 12. | ALA4628567 | F | In vivo agonist activity at D2S in rat assessed as suppression of gut motility administered daily for 7 days | Rattus norvegicus | 2 | organism-based format | Scientific Literature |
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