# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4626292 | B | Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spectrophotometric method | Mycobacterium tuberculosis | 36 | assay format | Scientific Literature | ||
2. | ALA4626293 | A | Inhibition of PTP1B (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spectrophotometric method | Homo sapiens | 36 | assay format | Scientific Literature | ||
3. | ALA4626294 | A | Inhibition of SHP2 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spectrophotometric method | Homo sapiens | 36 | assay format | Scientific Literature | ||
4. | ALA4626295 | A | Inhibition of SHP1 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spectrophotometric method | Homo sapiens | 25 | assay format | Scientific Literature | ||
5. | ALA4626330 | P | Lipophilicity, log D of the compound in pH 7.4 n-Octanol/PBS buffer at 100 uM measured after 8 hrs by LC-MS-based shake-flask method | 6 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4626331 | P | Kinetics solubility of the compound in pH 7.4 PBS buffer at 200 uM measured after 90 mins by HPLC analysis | 6 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA4626332 | A | Stability in CD1 mouse pooled liver microsomes assessed as CYP450-mediated metabolism by measuring half life in presence of NADPH by LC-MS/MS analysis | Mus musculus | 6 | microsome format | Scientific Literature |