# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4604290 | B | Inhibition of PDE1A (unknown origin) | Homo sapiens | 43 | single protein format | Scientific Literature | ||
2. | ALA4604292 | B | Binding affinity to PDE1A (unknown origin) assessed as association constant by SPR assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
3. | ALA4604293 | B | Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
4. | ALA4604294 | B | Binding affinity to PDE1A (unknown origin) assessed as target residence time by SPR assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
5. | ALA4604295 | B | Binding affinity to PDE1A (unknown origin) by SPR assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
6. | ALA4604296 | F | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
7. | ALA4604297 | F | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 5 uM relative to control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
8. | ALA4604298 | F | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 10 uM relative to control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
9. | ALA4604299 | F | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 25 uM relative to control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
10. | ALA4604300 | F | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 50 uM relative to control | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
11. | ALA4604301 | F | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 100 uM relative to control | Rattus norvegicus | 5 | organism-based format | Scientific Literature |