# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4604290 | Binding | Inhibition of PDE1A (unknown origin) | Homo sapiens | 43 | ALA4602654 | single protein format | Scientific Literature | |
2. | ALA4604292 | Binding | Binding affinity to PDE1A (unknown origin) assessed as association constant by SPR assay | Homo sapiens | 8 | ALA4602654 | single protein format | Scientific Literature | |
3. | ALA4604293 | Binding | Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay | Homo sapiens | 8 | ALA4602654 | single protein format | Scientific Literature | |
4. | ALA4604294 | Binding | Binding affinity to PDE1A (unknown origin) assessed as target residence time by SPR assay | Homo sapiens | 8 | ALA4602654 | single protein format | Scientific Literature | |
5. | ALA4604295 | Binding | Binding affinity to PDE1A (unknown origin) by SPR assay | Homo sapiens | 8 | ALA4602654 | single protein format | Scientific Literature | |
6. | ALA4604296 | Functional | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition | Rattus norvegicus | 5 | ALA4602654 | organism-based format | Scientific Literature | |
7. | ALA4604297 | Functional | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 5 uM relative to control | Rattus norvegicus | 5 | ALA4602654 | organism-based format | Scientific Literature | |
8. | ALA4604298 | Functional | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 10 uM relative to control | Rattus norvegicus | 5 | ALA4602654 | organism-based format | Scientific Literature | |
9. | ALA4604299 | Functional | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 25 uM relative to control | Rattus norvegicus | 5 | ALA4602654 | organism-based format | Scientific Literature | |
10. | ALA4604300 | Functional | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 50 uM relative to control | Rattus norvegicus | 5 | ALA4602654 | organism-based format | Scientific Literature | |
11. | ALA4604301 | Functional | Vasorelaxant activity in rat endothelium-intact thoracic aortic rings assessed as reduction in phenylephrine-induced contractions pretreated with phenylephrine followed by compound addition at 100 uM relative to control | Rattus norvegicus | 5 | ALA4602654 | organism-based format | Scientific Literature |