| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4603778 | B | Inhibition of ITK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assay | Homo sapiens | 36 | single protein format | Scientific Literature | ||
| 2. | ALA4603779 | B | Inhibition of BTK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assay | Homo sapiens | 24 | single protein format | Scientific Literature | ||
| 3. | ALA4603780 | B | Selectivity index, ratio of IC50 for BTK (unknown origin) to IC50 for ITK (unknown origin) by HTRF assay | Homo sapiens | 24 | assay format | Scientific Literature | ||
| 4. | ALA4603781 | B | Irreversible inhibition of binding of N-(2-((6-((but-3-yn-1-yloxy) (phenyl)methyl)-2-(6-(difluoromethyl)-1H-indazol-3-yl)-1H-indol-4-yl)oxy)ethyl)acrylamide to recombinant ITK (unknown origin) at 50 uM pretreated with compound prior to probe addition by fluorescence scan analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 5. | ALA4603782 | B | Time dependent inhibition of ITK (unknown origin) at 10 nM preincubated with compound for 10 to 60 mins prior to substrate TK and ATP addition by HTRF assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 6. | ALA4603783 | B | Binding affinity to ITK (unknown origin) using TK as substrate by HTRF assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 7. | ALA4603784 | B | Ratio of Kinact for ITK (unknown origin) to Ki for ITK (unknown origin) by HTRF assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 8. | ALA4603785 | B | Inhibition of recombinant human His-tagged FLT3 (564 to 958 residues) expressed in baculovirus expression system using Tyr02 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4603786 | B | Inhibition of recombinant human GST-tagged full length ITK expressed in baculovirus expression system using Tyr01 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA4603787 | B | Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using Tyr01 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA4603788 | B | Inhibition of tracer 222 binding to recombinant full length human His-tagged MAP3K7/MAP3K7IP1 expressed in baculovirus expression system at 0.6 uM incubated for 1 hr by Lanthascreen assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4603789 | B | Inhibition of recombinant human GST-tagged JAK3 catalytic domain (781 to 1124 residues) expressed in baculovirus expression system using Tyr06 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4603790 | B | Inhibition of recombinant human His-tagged full length ABL1 expressed in baculovirus expression system using Tyr02 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4603791 | B | Inhibition of recombinant human His-tagged full length Aurora B expressed in baculovirus expression system using Ser/Thr01 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4603792 | B | Inhibition of recombinant human His-tagged full length BLK expressed in baculovirus expression system using Tyr01 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4603793 | B | Inhibition of recombinant human C-terminal His-tagged full length LCK expressed in baculovirus expression system using Tyr02 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4603794 | B | Inhibition of recombinant human C-terminal His-tagged full length FYN expressed in baculovirus expression system using Tyr02 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA4603795 | B | Inhibition of recombinant human GST-tagged EGFR (668 to 1210 residues) expressed in baculovirus expression system using Tyr04 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4603796 | B | Inhibition of recombinant human His-tagged IGF1R (960 to 1397 residues) expressed in baculovirus expression system using Tyr01 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4603797 | B | Inhibition of recombinant human His-tagged full length CHEK2 expressed in baculovirus expression system using Ser/Thr07 peptide as substrate at 0.6 uM incubated for 1 hr by Z'lyte assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature |
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