| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4622626 | B | Inhibition of CBR1 (unknown origin) | Homo sapiens | 7 | ALA4619820 | single protein format | Scientific Literature | |
| 2. | ALA4622627 | B | Inhibition of recombinant AKR1C3 (unknown origin) assessed as reduction in S-tetralol-induced dehydrogenase activity by measuring NADPH level | Homo sapiens | 28 | ALA4619820 | single protein format | Scientific Literature | |
| 3. | ALA4622628 | B | Inhibition of recombinant AKR1C1 (unknown origin) assessed as reduction in S-tetralol-induced dehydrogenase activity by measuring NADPH level | Homo sapiens | 7 | ALA4619820 | single protein format | Scientific Literature | |
| 4. | ALA4622629 | B | Inhibition of recombinant AKR1C2 (unknown origin) assessed as reduction in S-tetralol-induced dehydrogenase activity by measuring NADPH level | Homo sapiens | 7 | ALA4619820 | single protein format | Scientific Literature | |
| 5. | ALA4622630 | B | Inhibition of recombinant AKR1C4 (unknown origin) assessed as reduction in S-tetralol-induced dehydrogenase activity by measuring NADPH level | Homo sapiens | 7 | ALA4619820 | single protein format | Scientific Literature | |
| 6. | ALA4622631 | B | Ratio of IC50 for inhibition of recombinant AKR1C1 (unknown origin) inhibition of recombinant AKR1C3 (unknown origin) | Homo sapiens | 7 | ALA4619820 | assay format | Scientific Literature | |
| 7. | ALA4622632 | B | Ratio of IC50 for inhibition of recombinant AKR1C2 (unknown origin) inhibition of recombinant AKR1C3 (unknown origin) | Homo sapiens | 7 | ALA4619820 | assay format | Scientific Literature | |
| 8. | ALA4622633 | B | Ratio of IC50 for inhibition of recombinant AKR1C4 (unknown origin) inhibition of recombinant AKR1C3 (unknown origin) | Homo sapiens | 7 | ALA4619820 | assay format | Scientific Literature | |
| 9. | ALA4622634 | B | Ratio of IC50 for inhibition of CBR1 (unknown origin) inhibition of recombinant AKR1C3 (unknown origin) | Homo sapiens | 7 | ALA4619820 | assay format | Scientific Literature | |
| 10. | ALA4622650 | B | Antagonistic activity at AR in human 22Rv1 cells assessed as reduction in cell number by CCK8 assay | Homo sapiens | 10 | ALA4619820 | cell-based format | Scientific Literature | |
| 11. | ALA4622651 | B | Agonistic activity at AR in human 22Rv1 cells assessed as effect on cell number at 1 nM by CCK8 assay | Homo sapiens | 16 | ALA4619820 | cell-based format | Scientific Literature | |
| 12. | ALA4622657 | F | Antitumor activity against human 22Rv1 cells xenografted in Balb/c nu/nu athymic mouse assessed as reduction in tumor volume at 100 mg/kg, ip dosed twice per week for 6 weeks | Homo sapiens | 1 | ALA4619820 | organism-based format | Scientific Literature | |
| 13. | ALA4622659 | F | Antitumor activity against human 22Rv1 cells xenografted in Balb/c nu/nu athymic mouse assessed as increase in necrotic region in tumor tissue at 100 mg/kg, ip dosed twice per week for 6 weeks by H and E staining dependent light microscopy based histopathological analysis | Homo sapiens | 1 | ALA4619820 | organism-based format | Scientific Literature | |
| 14. | ALA4622664 | T | Toxicity in Balb/c nu/nu athymic mouse xenografted with human 22Rv1 cells assessed as effect on lung histology at 100 mg/kg, ip dosed twice per week for 6 weeks by H and E staining dependent light microscopy based histopathological analysis | Mus musculus | 1 | ALA4619820 | organism-based format | Scientific Literature | |
| 15. | ALA4622665 | T | Toxicity in Balb/c nu/nu athymic mouse xenografted with human 22Rv1 cells assessed as effect on liver histology at 100 mg/kg, ip dosed twice per week for 6 weeks by H and E staining dependent light microscopy based histopathological analysis | Mus musculus | 1 | ALA4619820 | organism-based format | Scientific Literature | |
| 16. | ALA4622666 | T | Toxicity in Balb/c nu/nu athymic mouse xenografted with human 22Rv1 cells assessed as effect on kidney histology at 100 mg/kg, ip dosed twice per week for 6 weeks by H and E staining dependent light microscopy based histopathological analysis | Mus musculus | 1 | ALA4619820 | organism-based format | Scientific Literature | |
| 17. | ALA4622667 | T | Toxicity in Balb/c nu/nu athymic mouse xenografted with human 22Rv1 cells assessed as effect on body weight at 100 mg/kg, ip dosed twice per week for 6 weeks by H and E staining dependent light microscopy based histopathological analysis | Mus musculus | 1 | ALA4619820 | organism-based format | Scientific Literature |
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