# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4630124 | B | Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current by two-electrode voltage clamp method | Rattus norvegicus | 49 | cell-based format | Scientific Literature | ||
2. | ALA4630125 | B | Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current by two-electrode voltage clamp method | Rattus norvegicus | 49 | cell-based format | Scientific Literature | ||
3. | ALA4630126 | B | Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current by measuring log of doubling concentration by two-electrode voltage clamp method | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
4. | ALA4630127 | B | Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current by measuring log of doubling concentration by two-electrode voltage clamp method | Rattus norvegicus | 28 | cell-based format | Scientific Literature | ||
5. | ALA4630128 | P | Aqueous solubility of the compound at pH 7.4 after 30 mins by nephelometric analysis | 14 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4630129 | B | Positive allosteric modulation of recombinant rat GluN1a/GluN2C receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current at 30 uM by two-electrode voltage clamp method relative to control | Rattus norvegicus | 49 | cell-based format | Scientific Literature | ||
7. | ALA4630130 | B | Positive allosteric modulation of recombinant rat GluN1a/GluN2D receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current at 30 uM by two-electrode voltage clamp method relative to control | Rattus norvegicus | 49 | cell-based format | Scientific Literature | ||
8. | ALA4630151 | A | Positive allosteric modulation of recombinant rat GluN1a/GluN2A receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current at 10 to 30 uM by two-electrode voltage clamp method relative to control | Rattus norvegicus | 47 | cell-based format | Scientific Literature | ||
9. | ALA4630152 | A | Positive allosteric modulation of recombinant rat GluN1a/GluN2B receptor expressed in Xenopus laevis oocytes assessed as increase in glycine/L-glutamate-induced channel current at 10 to 30 uM by two-electrode voltage clamp method relative to control | Rattus norvegicus | 47 | cell-based format | Scientific Literature |