| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4605122 | B | Inhibition of recombinant human full-length N-terminal His-tagged CDK6/cyclinD3 expressed in baculovirus infected Sf9 insect cells using histone H1 as substrate measured after 60 mins by ADP-glo assay | Homo sapiens | 54 | cell-based format | Scientific Literature | ||
| 2. | ALA4605123 | B | Inhibition of recombinant human full-length N-terminal GST-tagged CDK9/cyclinK expressed in baculovirus infected Sf9 insect cells using PDKtide as substrate measured after 120 mins by ADP-glo assay | Homo sapiens | 60 | cell-based format | Scientific Literature | ||
| 3. | ALA4605124 | A | Inhibition of recombinant human full-length N-terminal GST-tagged CDK2/cyclinA2 expressed in baculovirus infected Sf9 insect cells using histone H1 as substrate measured after 10 mins by ADP-glo assay | Homo sapiens | 53 | cell-based format | Scientific Literature | ||
| 4. | ALA4605125 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay | Homo sapiens | 54 | cell-based format | Scientific Literature | ||
| 5. | ALA4605126 | F | Antiproliferative activity against human Jurkat cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay | Homo sapiens | 54 | cell-based format | Scientific Literature | ||
| 6. | ALA4605127 | F | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay | Homo sapiens | 54 | cell-based format | Scientific Literature | ||
| 7. | ALA4605128 | A | Cytotoxicity against human L02 cells assessed as inhibition of cell proliferation measured after 48 hrs by CCK8 assay | Homo sapiens | 53 | cell-based format | Scientific Literature | ||
| 8. | ALA4605130 | B | Inhibition of recombinant human full-length N-terminal GST-tagged CDK3/cyclinE1 expressed in baculovirus infected Sf9 insect cells at 1 uM using histone H1 as substrate measured after 10 to 60 mins by ADP-glo assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4605131 | A | Inhibition of recombinant human full-length N-terminal GST-tagged CDK5/p35 expressed in baculovirus infected Sf9 insect cells at 1 uM using histone H1 as substrate measured after 10 to 60 mins by ADP-glo assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4605132 | B | Inhibition of recombinant human GST-tagged/His-tagged CDK11 (1 to 502 residues)/cyclinC (1 to 283 residues) expressed in insect cells at 1 uM using PAK1 (148 to 210 residues) as substrate measured after 10 to 60 mins by ADP-glo assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4605133 | B | Selectivity ratio of IC50 for recombinant human full-length N-terminal His-tagged CDK6/cyclinD3 expressed in baculovirus infected Sf9 insect cells to IC50 for recombinant human full-length N-terminal GST-tagged CDK9/cyclinK expressed in baculovirus infected Sf9 insect cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4605134 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G0/G1 phase at 4 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 57.65%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4605135 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 4 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 26.45%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4605136 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G2/M phase at 4 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 15.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4605137 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G0/G1 phase at 8 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 57.65%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4605138 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 8 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 26.45%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4605139 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G2/M phase at 8 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 15.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4605140 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G0/G1 phase at 12 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 57.65%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4605141 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at S phase at 12 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 26.45%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4605142 | F | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation at G2/M phase at 12 uM measured after 48 hrs by propidium iodide staining based flow cytometry (Rvb = 15.9%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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