| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4614066 | Functional | Inhibition of 3-alpha-diol conversion to 5-alpha-dihydrotestosterone in human LAPC4 cells assessed in 200000 cells measured after 24 hrs using [14C]-3-alpha-diol/[14C]-3-beta-diol (9:1) as non-radiolabeled/radiolabeled 20:1 mixture by TLC analysis | Homo sapiens | 7 | ALA4613219 | cell-based format | Scientific Literature | |
| 2. | ALA4733681 | Binding | Inhibition of human 17-beta-HSD10 expressed in HEK293 cells assessed as reduction in oxidation of [14C]-estradiol to [14C]-estrone incubated for 40 hrs by thin layer chromatography | Homo sapiens | 15 | ALA4732072 | cell-based format | Scientific Literature | |
| 3. | ALA4733682 | Binding | Potency index, ratio of (3R,5S,8R,9S,10S,13S,14S)-3-hydroxy-3-((4-(3-methoxybenzyl)piperazin-1-yl)methyl)-10,13-dimethyltetradecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one IC50 to compound IC50 for inhibition of human 17-beta-HSD10 expressed in HEK-293 cells | Homo sapiens | 14 | ALA4732072 | cell-based format | Scientific Literature |
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