# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4605536 | Binding | Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay | Homo sapiens | 39 | ALA4602704 | cell-based format | Scientific Literature | |
2. | ALA4605537 | Binding | Inhibition of GLUT3 in SLC2A1-deficient human DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay | Homo sapiens | 40 | ALA4602704 | cell-based format | Scientific Literature | |
3. | ALA4605548 | ADME | Apparent permeability across apical to basolateral in human Caco2 cells at 5 uM | Homo sapiens | 11 | ALA4602704 | cell-based format | Scientific Literature | |
4. | ALA4605549 | ADME | Apparent permeability across basolateral to apical in human Caco2 cells at 5 uM | Homo sapiens | 11 | ALA4602704 | cell-based format | Scientific Literature | |
5. | ALA4605557 | ADME | Ratio of drug level in CD-1 mouse brain to plasma at 100 mg/kg, po incubated for 1 hr | Mus musculus | 10 | ALA4602704 | organism-based format | Scientific Literature |