# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4618010 | B | Displacement of [3H]nicotinic acid from GRP109A receptor (unknown origin) expressed in 293-EBNA cell membranes by liquid scintillation analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
2. | ALA4618011 | F | Agonist activity at GPR109A receptor (unknown origin) expressed in HEK293T cell membranes after 30 mins by [35S]GTPgammaS binding based microbeta scintillation counting analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
3. | ALA4618012 | B | Agonist activity at GPR109A receptor in human adipocytes assessed as inhibition of lipolysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
4. | ALA4618013 | F | Invivo activation of human GPR109A expressed in Sprague-Dawley rat assessed as change in plasma NEFA levels at 10 mg/kg, po after 0.5 hrs by Wako-reagent based C-test (Rvb = 0%) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
5. | ALA4618014 | F | Invivo activation of human GPR109A expressed in Sprague-Dawley rat assessed as change in plasma NEFA levels at 30 mg/kg, po after 0.5 hrs by Wako-reagent based C-test (Rvb = 0%) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA4618016 | F | Invivo activation of human GPR109A expressed in Sprague-Dawley rat assessed as change in plasma NEFA levels at 10 mg/kg, po after 3 hrs by Wako-reagent based C-test (Rvb = 0%) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
7. | ALA4618017 | F | Invivo activation of human GPR109A expressed in Sprague-Dawley rat assessed as change in plasma NEFA levels at 30 mg/kg, po after 3 hrs by Wako-reagent based C-test (Rvb = 0%) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA4618019 | A | AUC (0 to 7 hrs) in rat at 10 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature |