# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4628237 | A | Drug reactivity against cysteamine in pH 7.4 PBS buffer assessed as half life at 250 uM measured up to 72 hrs by HPLC-MS/MS analysis | 13 | ALA4627297 | assay format | Scientific Literature | ||
2. | ALA4628238 | A | Drug reactivity against N-bezoyl-cysteamine in pH 7.4 PBS buffer assessed as half life at 250 uM measured up to 72 hrs by HPLC analysis | 13 | ALA4627297 | assay format | Scientific Literature | ||
3. | ALA4628239 | A | Drug reactivity against cysteine in pH 7.4 PBS buffer assessed as half life at 250 uM measured up to 72 hrs by HPLC-MS/MS analysis | 13 | ALA4627297 | assay format | Scientific Literature | ||
4. | ALA4628240 | A | Drug reactivity against N-acetyl-cysteine in pH 7.4 PBS buffer assessed as half life at 250 uM measured up to 72 hrs by HPLC-MS analysis | 13 | ALA4627297 | assay format | Scientific Literature | ||
5. | ALA4628241 | A | Drug reactivity against N-benzoyl-cysteine in pH 7.4 PBS buffer assessed as half life at 250 uM measured up to 72 hrs by HPLC-MS analysis | 13 | ALA4627297 | assay format | Scientific Literature | ||
6. | ALA4628242 | A | Drug reactivity against glutathione in pH 7.4 PBS buffer assessed as half life at 250 uM measured up to 72 hrs by HPLC analysis | 13 | ALA4627297 | assay format | Scientific Literature | ||
7. | ALA4628243 | A | Drug reactivity against N-benzoyl-glutathione in pH 7.4 PBS buffer assessed as half life at 250 uM measured up to 72 hrs by HPLC-MS/MS analysis | 13 | ALA4627297 | assay format | Scientific Literature | ||
8. | ALA4628244 | P | Solubility of the compound in pH 7.4 PBS buffer | 13 | ALA4627297 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA5231765 | P | Thiol reactivity of compound assessed as kinetic rate constant by LC-MS analysis | 24 | ALA5230128 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA5231766 | P | Thiol reactivity of compound assessed as half life by LC-MS analysis | 23 | ALA5230128 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA5231767 | P | Aqueous stability of the compound assessed as compound degradation by measuring kinetic constant measured after 72 hrs by LC-MS analysis | 24 | ALA5230128 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA5231768 | P | Aqueous stability of the compound assessed as compound degradation by measuring half life measured after 72 hrs by LC-MS analysis | 24 | ALA5230128 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA5231769 | B | Inhibition of BTK (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative to control | Homo sapiens | 24 | ALA5230128 | single protein format | Scientific Literature | |
14. | ALA5231770 | B | Inhibition of ERK2 (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative to control | Homo sapiens | 24 | ALA5230128 | single protein format | Scientific Literature | |
15. | ALA5231771 | B | Inhibition of RSK2 (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative to control | Homo sapiens | 25 | ALA5230128 | single protein format | Scientific Literature | |
16. | ALA5231772 | B | Inhibition of MAP2K4 (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative to control | Homo sapiens | 25 | ALA5230128 | single protein format | Scientific Literature | |
17. | ALA5231773 | B | Inhibition of JAK3 (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative to control | Homo sapiens | 24 | ALA5230128 | single protein format | Scientific Literature | |
18. | ALA5231774 | B | Inhibition of MELK (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative to control | Homo sapiens | 24 | ALA5230128 | single protein format | Scientific Literature | |
19. | ALA5231776 | B | Inhibition of JAK3 (unknown origin) incubated for 45 mins by LC-MS/MS analysis | Homo sapiens | 29 | ALA5230128 | single protein format | Scientific Literature |