| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4627529 | B | Binding affinity to 5' FAM/3' TAMRA (G4C2)8 G-quadruplex DNA (unknown origin) by FRET assay | Not specified | 6 | nucleic acid format | Scientific Literature | ||
| 2. | ALA4680567 | B | Inhibition of recombinant human His-tagged PRMT1 expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H4-20 as substrate incubated for 8 mins in presence of [3H]-SAM cofactor by scintillation proximity assay | Homo sapiens | 32 | assay format | Scientific Literature | ||
| 3. | ALA4680568 | B | Inhibition of recombinant human His-tagged PRMT3 expressed in Escherichia coli BL21 (DE3) using biotin-labeled SMD1 as substrate incubated for 10 mins in presence of [3H]-SAM cofactor by scintillation proximity assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 4. | ALA4680569 | B | Inhibition of recombinant GST-tagged CARM1 (unknown origin) expressed in Escherichia coli using histone H3.3 peptide as substrate incubated for 120 mins in presence of [3H]-SAM cofactor by radioactive filter plate assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 5. | ALA4680570 | B | Inhibition of recombinant GST-tagged CARM1 (unknown origin) expressed in Escherichia coli assessed as residual activity at 10 uM using histone H3.3 peptide as substrate incubated for 120 mins in presence of [3H]-SAM cofactor by radioactive filter plate assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4680571 | B | Inhibition of PRMT5/MEP50 (unknown origin) using biotin-labeled histone H4-20 peptide as substrate incubated for 8 mins in presence of [3H]-SAM cofactor by scintillation proximity assay | Homo sapiens | 5 | protein complex format | Scientific Literature | ||
| 7. | ALA4680572 | B | Inhibition of PRMT5/MEP50 (unknown origin) assessed as residual activity at 10 uM using biotin-labeled histone H4-20 peptide as substrate incubated for 8 mins in presence of [3H]-SAM cofactor by scintillation proximity assay relative to control | Homo sapiens | 1 | protein complex format | Scientific Literature | ||
| 8. | ALA4680573 | B | Inhibition of PRMT6 (unknown origin) using biotin-labeled SMD1 as substrate incubated for 30 mins in presence of [3H]-SAM cofactor by scintillation proximity assay | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 9. | ALA4680574 | B | Inhibition of PRMT6 (unknown origin) assessed as residual activity at 10 uM using biotin-labeled SMD1 as substrate incubated for 30 mins in presence of [3H]-SAM cofactor by scintillation proximity assay relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA4680575 | B | Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli using biotin-labeled SMD1 as substrate incubated for 120 mins in presence of [3H]-SAM cofactor by scintillation proximity assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 11. | ALA4680576 | B | Inhibition of recombinant GST-tagged PRMT7 (unknown origin) expressed in Escherichia coli assessed as residual activity at 10 uM using biotin-labeled SMD1 as substrate incubated for 120 mins in presence of [3H]-SAM cofactor by scintillation proximity assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4680577 | B | Inhibition of recombinant His-tagged human PRMT8 expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H4-20 peptide as substrate incubated for 8 mins in presence of [3H]-SAM cofactor by scintillation proximity assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 13. | ALA4680578 | B | Inhibition of recombinant His-tagged human G9a expressed in Escherichia coli BL21 (DE3) using biotin-labeled histone H3-20 peptide as substrate incubated for 30 mins in presence of [3H]-SAM cofactor by scintillation proximity assay | Homo sapiens | 5 | assay format | Scientific Literature | ||
| 14. | ALA4680579 | B | Inhibition of recombinant His-tagged human G9a expressed in Escherichia coli BL21 (DE3) assessed as residual activity at 10 uM using biotin-labeled histone H3-20 peptide as substrate incubated for 30 mins in presence of [3H]-SAM cofactor by scintillation proximity assay relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4680580 | B | Non-competitive inhibition of recombinant His-tagged PRMT1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using varying levels of biotin-labeled histone H4-20 as substrate | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4680581 | B | Non-competitive inhibition of recombinant His-tagged PRMT1 (unknown origin) expressed in Escherichia coli BL21 (DE3) using varying levels of [3H]-SAM as cofactor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4680582 | F | Antiproliferative activity against human MEG-01 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4680583 | F | Antiproliferative activity against human CMK cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4680584 | F | Antiproliferative activity against human K562 cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4680585 | F | Antiproliferative activity against human HEL cells assessed as inhibition of cell growth measured after 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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