# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4629122 | Binding | Binding affinity to HSP90 (unknown origin) by Line weaver-Burk plot analysis | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature | |
2. | ALA4629123 | Functional | Antiproliferative activity against BRCA1-deficient human MX1 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
3. | ALA4629124 | Functional | Antiproliferative activity against BRCA1-deficient human HCC1937 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
4. | ALA4629125 | Functional | Antiproliferative activity against BRCA2-deficient human Capan1 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
5. | ALA4629126 | Functional | Antiproliferative activity against BRCA-proficient human MCF7 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
6. | ALA4629127 | Functional | Antiproliferative activity against BRCA-proficient human SKBR3 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
7. | ALA4629128 | Functional | Antiproliferative activity against BRCA-proficient human MDA-MB-231 cells after 48 hrs by MTT assay | Homo sapiens | 12 | ALA4627353 | cell-based format | Scientific Literature | |
8. | ALA4629129 | Functional | Potency index, ratio of compound IC50 to Olaparib IC50 for antiproliferative activity against human MCF7 cells | Homo sapiens | 2 | ALA4627353 | cell-based format | Scientific Literature | |
9. | ALA4629130 | Binding | Inhibition of PARP in human MCF7 cells assessed as down regulation of PAR at 1 to 100 uM in presence of adriamycin by western blotting analysis | Homo sapiens | 3 | ALA4627353 | cell-based format | Scientific Literature | |
10. | ALA4629133 | Binding | Binding affinity to HSP90 (unknown origin) assessed as Stern-Volmer quenching constant by Stern-Volmer plot analysis | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature | |
11. | ALA4629134 | Binding | Binding affinity to HSP90 (unknown origin) assessed as quenching constant by Stern-Volmer plot analysis | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature | |
12. | ALA4629136 | Binding | Binding affinity to HSP90 (unknown origin) by fluorescence quenching method | Homo sapiens | 4 | ALA4627353 | protein format | Scientific Literature |