| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4606092 | B | Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring inhibition of cell proliferation at 1 uM incubated for 48 hrs by SRB assay (Rvb = 5.3 +/- 3 %) | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 2. | ALA4606093 | B | Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring DOX IC50 at 1 uM incubated for 48 hrs by SRB assay (Rvb = 33.39 +/- 7.08 uM) | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 3. | ALA4606094 | B | Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as potentiation of DOX-induced cytotoxicity by measuring change in DOX IC50 at 1 uM incubated for 48 hrs by SRB assay relative to DOX alone | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
| 4. | ALA4606095 | A | Cytotoxicity against human SW620/AD300 cells assessed as cell growth inhibition at 10 uM incubated for 48 hrs by SRB assay relative to control | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA4606096 | B | Reversal of Pgp-mediated DOX resistance in human SW620/AD300 cells assessed as concentration required to show half of DOX IC50 incubated for 48 hrs by SRB assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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