| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4625931 | B | Inhibition of His-tagged BLM (642 to 1296 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction in DNA unwinding activity using 5'-biotin-labeled forked DNA as substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by electrophoretic mobility shift assay | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 2. | ALA4625936 | F | Cytotoxicity against human HCT116 cells by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA4625938 | B | Inhibition of BLM in human HCT116 cells assessed as down regulation of HRR level at 0.5 uM measured after 24 hrs by luciferase reporter gene assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 4. | ALA4625939 | B | Inhibition of BLM in human HCT116 cells assessed as increase in gamma-H2AX level at 2 uM measured after 24 hrs by Western blot analysis | Homo sapiens | 6 | cell-based format | Scientific Literature |
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