# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4620800 | F | Antagonist activity at PTHR1 (unknown origin) expressed in CHOK1 cells co-expressing Gs/Gq assessed as reduction in human PTH (1 to 34 residues)-induced cAMP level incubated for 30 mins | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
2. | ALA4620801 | A | Metabolic stability in rat liver microsomes assessed as parent compound remaining at 1 uM in presence of NADPH generating system measured after 20 mins by LC-MS/MS analysis | Rattus norvegicus | 12 | microsome format | Scientific Literature | ||
3. | ALA4620802 | P | Solubility of the compound in JP1 fluid at pH 1.2 | 9 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA4620803 | P | Solubility of the compound in JP2 buffer at pH 6.8 | 9 | small-molecule physicochemical format | Scientific Literature |