| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4604217 | B | Protac activity at CRBN/CDK2 in AR-negative human PC3 cells assessed as induction of CDK2 protein degradation at 1 uM after 12 hrs by Western blot analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA4604218 | B | Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as induction of CDK2 protein degradation at 5 uM after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4604219 | B | Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 5 uM after 12 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4604222 | B | Protac activity at CRBN/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 1 uM after 12 hrs by Western blot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 5. | ALA4604226 | F | Antiproliferative activity against AR-negative human PC3 cells assessed as reduction in cell viability after 5 days by CCK8 assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 6. | ALA4604257 | B | Protac activity at CRBN/CDK5 in AR-negative human PC3 cells assessed as induction of CDK5 protein degradation at 1 uM after 12 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4604270 | B | Protac activity at CRBN/CDK2/CDK9 in AR-negative human PC3 cells assessed as induction of CDK9 protein degradation at 30 uM after 12 hrs by Western blot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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