| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4624407 | P | Solubility of the compound in water | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA4624408 | P | Solubility of the compound in water relative to 17-AAG | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA4624409 | F | Antiproliferative activity against human CNE2Z cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4624410 | F | Antiproliferative activity against human SMMC7721 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4624411 | F | Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA4624412 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA4624413 | F | Antiproliferative activity against human SW480 cells assessed as cell growth inhibition by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4624414 | B | Inhibition of HSP90 ATPase activity (unknown origin) malachite-green phosphate assay | Homo sapiens | 1 | protein format | Scientific Literature | ||
| 9. | ALA4624415 | B | Inhibition of HSP90 in human CNE2Z cells assessed as downregulation of Akt expression at 10 to 40 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4624416 | B | Inhibition of HSP90 in human CNE2Z cells assessed as downregulation of Her-2 expression at 10 to 40 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4624417 | B | Inhibition of HSP90 in human CNE2Z cells assessed as downregulation of c-Raf expression at 10 to 40 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4624418 | B | Inhibition of HSP90 in human CNE2Z cells assessed as downregulation of Bcl2 expression at 10 to 40 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4624419 | B | Inhibition of HSP90 in human CNE2Z cells assessed as downregulation of HIF-1alpha expression at 10 to 40 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4624420 | F | Antitumor activity against human CNE2Z cells xenografted in nude mouse assessed as reduction in tumor volume at 1 mg/kg, ip administered for 19 days relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4624421 | T | Toxicity in nude mouse xenografted with human CNE2Z cells assessed as effect on body weight at 1 mg/kg, ip administered for 19 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4624422 | T | Toxicity in nude mouse xenografted with human CNE2Z cells assessed as effect on liver at 1 mg/kg, ip administered for 19 days by hematoxylin and eosin staining based assay | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4624423 | T | Toxicity in nude mouse xenografted with human CNE2Z cells assessed as effect on lung at 1 mg/kg, ip administered for 19 days by hematoxylin and eosin staining based assay | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4624424 | T | Toxicity in nude mouse xenografted with human CNE2Z cells assessed as effect on kidney at 1 mg/kg, ip administered for 19 days by hematoxylin and eosin staining based assay | Mus musculus | 1 | organism-based format | Scientific Literature |
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