#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4622176	A	Fraction unbound in human plasma	Homo sapiens	16		cell-free format	Scientific Literature
2.	ALA4622177	A	Fraction unbound in mouse plasma	Mus musculus	16		cell-free format	Scientific Literature
3.	ALA4622178	A	Fraction unbound in 10% fetal calf serum	Bos taurus	2		cell-free format	Scientific Literature
4.	ALA4622179	B	Modulation of gamma secretase in human H4 cells over expressing human APP695 harboring K595N/M596L Swedish double mutant assessed as reduction in Abeta42 production after 24 hrs by Alphalisa assay	Homo sapiens	21		cell-based format	Scientific Literature
5.	ALA4622180	B	Modulation of mouse gamma secretase assessed as reduction in Abeta42 production	Mus musculus	13		assay format	Scientific Literature
6.	ALA4622181	F	In vivo modulation of gamma secretase in APP-Swedish transgenic mouse assessed as reduction in Abeta42 production by measuring remaining Abeta42 level at 1 mg/kg, po measured after 4 hrs by ELISA or AlphaLISA assay relative to control	Mus musculus	3		organism-based format	Scientific Literature
7.	ALA4622182	F	In vivo modulation of gamma secretase in APP-Swedish transgenic mouse assessed as reduction in Abeta42 production by measuring remaining Abeta42 level at 3 mg/kg, po measured after 4 hrs by ELISA or AlphaLISA assay relative to control	Mus musculus	4		organism-based format	Scientific Literature
8.	ALA4622183	F	In vivo modulation of gamma secretase in APP-Swedish transgenic mouse assessed as reduction in Abeta42 production by measuring remaining Abeta42 level at 10 mg/kg, po measured after 4 hrs by ELISA or AlphaLISA assay relative to control	Mus musculus	5		organism-based format	Scientific Literature
9.	ALA4622184	P	Octanol/water distribution co-efficient, log D of the compound at pH 7.4		20		small-molecule physicochemical format	Scientific Literature
10.	ALA4622185	P	Solubility of compound by lyophilisation solubility assay		20		small-molecule physicochemical format	Scientific Literature
11.	ALA4622186	A	Clearance in human hepatocytes assessed per million cells	Homo sapiens	15		cell-based format	Scientific Literature
12.	ALA4622187	A	Clearance in mouse hepatocytes assessed per million cells	Mus musculus	16		cell-based format	Scientific Literature
13.	ALA4622188	B	Inhibition of human Pgp assessed as efflux ratio	Homo sapiens	6		single protein format	Scientific Literature
14.	ALA4622189	B	Inhibition of human ERG	Homo sapiens	6		single protein format	Scientific Literature
15.	ALA4622190	B	Inhibition of mouse Pgp assessed as efflux ratio	Mus musculus	6		assay format	Scientific Literature
16.	ALA4622191	A	Binding affinity to PIK4CB (unknown origin)	Homo sapiens	10		single protein format	Scientific Literature
17.	ALA4622193	F	In vivo modulation of gamma secretase in APP-Swedish transgenic mouse assessed as reduction in Abeta42 production by measuring remaining Abeta42 level at 0.3 mg/kg, po measured after 4 hrs by ELISA or AlphaLISA assay relative to control	Mus musculus	1		organism-based format	Scientific Literature
18.	ALA4622207	F	In vivo modulation of gamma secretase in po dosed APP-Swedish transgenic mouse assessed as reduction in total Abeta42 production level in brain administered as single dose by ELISA or AlphaLISA assay	Mus musculus	3		organism-based format	Scientific Literature
19.	ALA4622211	A	Phototoxicity in human Keratinocytes in presence of UVA at 320 to 400 nm	Homo sapiens	6		cell-based format	Scientific Literature
20.	ALA4622212	T	Dark toxicity in human Melanocytes assessed as reduction in cell viability	Homo sapiens	1		cell-based format	Scientific Literature