#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4708483	B	Inhibition of IDH2 R140Q mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-ketoglutarate and NADPH as substrate preincubated with enzyme for 15 mins followed by substrate addition by fluorescence based assay	Homo sapiens	36	ALA4706511	single protein format	Scientific Literature
2.	ALA4708484	B	Inhibition of IDH2 R172K mutant (unknown origin) assessed as reduction in NADPH consumption using alpha-ketoglutarate and NADPH as substrate preincubated with enzyme for 15 mins followed by substrate addition by fluorescence based assay	Homo sapiens	36	ALA4706511	single protein format	Scientific Literature
3.	ALA4708485	B	Inhibition of wild type IDH2 (unknown origin) assessed as reduction in NADPH production using sodium(D)-isocitrate and NADP as substrate preincubated with enzyme for 15 mins followed by substrate addition by fluorescence based assay	Homo sapiens	34	ALA4706511	single protein format	Scientific Literature
4.	ALA4708486	F	Cytotoxicity aganist human TF-1 cells harboring IDH2 mutant	Homo sapiens	7	ALA4706511	cell-based format	Scientific Literature
5.	ALA4708488	B	Inhibition of human IDH2 R140Q mutant expressed in TF-1 cells assessed as inhibition of 2-HG production at 0.1 uM incubated for 48 hrs by LC-MS/MS analysis	Homo sapiens	22	ALA4706511	cell-based format	Scientific Literature
6.	ALA4708489	A	Metabolic stability in human liver microsomes assessed as parent compound remaining at 100 ug/ml measured after 15 mins in presence of NADPH by LC-MS analysis	Homo sapiens	6	ALA4706511	microsome format	Scientific Literature
7.	ALA4708490	A	Metabolic stability in human liver microsomes assessed as parent compound remaining at 100 ug/ml measured after 45 mins in presence of NADPH by LC-MS analysis	Homo sapiens	6	ALA4706511	microsome format	Scientific Literature
8.	ALA4708491	A	Metabolic stability in human liver microsomes assessed as parent compound remaining at 100 ug/ml measured after 90 mins in presence of NADPH by LC-MS analysis	Homo sapiens	6	ALA4706511	microsome format	Scientific Literature
9.	ALA4708492	B	Inhibition of human IDH2 R140Q mutant expressed in TF-1 cells assessed as inhibition of 2-HG production at 10 uM incubated for 48 hrs by LC-MS/MS analysis	Homo sapiens	22	ALA4706511	cell-based format	Scientific Literature