# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4675230 | B | Inhibition of human CYP1A1 expressed in HEK293 cells assessed as reduction in CYP1A1 mediated B[alpha]P-7,8- dihydrodiol induced-toxicity by measuring EC50 at 3 times of IC50 concentration by MTT assay relative to control | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA4675231 | B | Inhibition of human CYP1A1 expressed in human HEK293 cells at 10 uM using 7-ethoxyresorufin as substrate preincubated for 30 mins followed by substrate additon and measured after 60 mins by fluorescence based assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA4675233 | B | Inhibition of human CYP1A1 expressed in sacchrosomes at 10 uM using 7-ethoxyresorufin as substrate by fluorescence based assay relative to control | Homo sapiens | 4 | assay format | Scientific Literature | ||
4. | ALA4675251 | A | Inhibition of human CYP1B1 expressed in human HEK293 cells using 7-ethoxyresorufin as substrate preincubated for 30 mins followed by substrate additon and measured after 60 mins by fluorescence based assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
5. | ALA4675252 | B | Inhibition of human CYP1A1 expressed in human HEK293 cells using 7-ethoxyresorufin as substrate preincubated for 30 mins followed by substrate additon and measured after 60 mins by fluorescence based assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
6. | ALA4675253 | A | Inhibition of human CYP1B1 expressed in sacchrosomes using 7-ethoxyresorufin as substrate by fluorescence based assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
7. | ALA4675254 | B | Inhibition of human CYP1A1 expressed in sacchrosomes using 7-ethoxyresorufin as substrate by fluorescence based assay | Homo sapiens | 10 | assay format | Scientific Literature |