# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4678308 | Binding | Inhibition of human erythrocytes CuZn-SOD by UV-VIS spectrophotometric method | Homo sapiens | 2 | ALA4673334 | tissue-based format | Scientific Literature | |
2. | ALA4678309 | Binding | Inhibition of Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form Fe-SOD by UV-VIS spectrophotometric method | Trypanosoma cruzi | 2 | ALA4673334 | assay format | Scientific Literature | |
3. | ALA4678310 | Functional | Inhibition of nucleic acid level in Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form at IC25 concentration after 72 hrs by Rho (FITC-A) staining based flow cytometric analysis | Trypanosoma cruzi | 3 | ALA4673334 | assay format | Scientific Literature | |
4. | ALA4678311 | Functional | Inhibition of mitochondrial membrane potential in Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form at IC25 concentration after 72 hrs by Rho (FITC-A) staining based flow cytometric analysis | Trypanosoma cruzi | 4 | ALA4673334 | assay format | Scientific Literature | |
5. | ALA4678312 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of D-lactate level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | ALA4673334 | organism-based format | Scientific Literature | |
6. | ALA4678313 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of L-alanine level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | ALA4673334 | organism-based format | Scientific Literature | |
7. | ALA4678314 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of acetate level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | ALA4673334 | organism-based format | Scientific Literature | |
8. | ALA4678315 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of pyruvate level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | ALA4673334 | organism-based format | Scientific Literature | |
9. | ALA4678316 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of succinic acid level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | ALA4673334 | organism-based format | Scientific Literature | |
10. | ALA4678317 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of ethanol end product level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | ALA4673334 | organism-based format | Scientific Literature | |
11. | ALA4678318 | Functional | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of glycerol level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | ALA4673334 | organism-based format | Scientific Literature | |
12. | ALA4678319 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in weight at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured up to 145 days post infection | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
13. | ALA4678320 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in weight at 20 mg/kg, po administered for 5 days starting at 9 days post infection and measured up to 145 days post infection | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
14. | ALA4678321 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in survival at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured up to 145 days post infection | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
15. | ALA4678322 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in survival at 20 mg/kg, po administered for 5 days starting at 9 days post infection and measured up to 145 days post infection | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
16. | ALA4678323 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on ALP level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
17. | ALA4678324 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on total bilirubin level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
18. | ALA4678325 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on ALT/GPT level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
19. | ALA4678326 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on ASG/GOT level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature | |
20. | ALA4678327 | Toxicity | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on LDH level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | ALA4673334 | organism-based format | Scientific Literature |