# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4678308 | B | Inhibition of human erythrocytes CuZn-SOD by UV-VIS spectrophotometric method | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
2. | ALA4678309 | B | Inhibition of Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form Fe-SOD by UV-VIS spectrophotometric method | Trypanosoma cruzi | 2 | assay format | Scientific Literature | ||
3. | ALA4678310 | F | Inhibition of nucleic acid level in Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form at IC25 concentration after 72 hrs by Rho (FITC-A) staining based flow cytometric analysis | Trypanosoma cruzi | 3 | assay format | Scientific Literature | ||
4. | ALA4678311 | F | Inhibition of mitochondrial membrane potential in Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form at IC25 concentration after 72 hrs by Rho (FITC-A) staining based flow cytometric analysis | Trypanosoma cruzi | 4 | assay format | Scientific Literature | ||
5. | ALA4678312 | F | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of D-lactate level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
6. | ALA4678313 | F | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of L-alanine level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
7. | ALA4678314 | F | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of acetate level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
8. | ALA4678315 | F | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of pyruvate level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
9. | ALA4678316 | F | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of succinic acid level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
10. | ALA4678317 | F | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of ethanol end product level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
11. | ALA4678318 | F | Antitrypanosomal activity against Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) epimastigote form assessed as disruption of glycerol level at IC25 concentration incubated for 72 hrs by NMR spectrometric analysis | Trypanosoma cruzi | 2 | organism-based format | Scientific Literature | ||
12. | ALA4678319 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in weight at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured up to 145 days post infection | Mus musculus | 3 | organism-based format | Scientific Literature | ||
13. | ALA4678320 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in weight at 20 mg/kg, po administered for 5 days starting at 9 days post infection and measured up to 145 days post infection | Mus musculus | 3 | organism-based format | Scientific Literature | ||
14. | ALA4678321 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in survival at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured up to 145 days post infection | Mus musculus | 3 | organism-based format | Scientific Literature | ||
15. | ALA4678322 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as reduction in survival at 20 mg/kg, po administered for 5 days starting at 9 days post infection and measured up to 145 days post infection | Mus musculus | 3 | organism-based format | Scientific Literature | ||
16. | ALA4678323 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on ALP level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | organism-based format | Scientific Literature | ||
17. | ALA4678324 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on total bilirubin level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | organism-based format | Scientific Literature | ||
18. | ALA4678325 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on ALT/GPT level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | organism-based format | Scientific Literature | ||
19. | ALA4678326 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on ASG/GOT level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | organism-based format | Scientific Literature | ||
20. | ALA4678327 | T | Toxicity in BALB/c mouse infected with Trypanosomal Trypanosoma cruzi MHOM/Pe/2011/Arequipa(DTU V) assessed as effect on LDH level at 20 mg/kg, po administered for 5 days starting at 100 days post infection and measured after 2 days post treatment | Mus musculus | 3 | organism-based format | Scientific Literature |