# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4681809 | Binding | Inhibition of protein interaction between beta-catenin (unknown origin)/BCL9 in human SW480 cells transfected with beta-catenin assessed as reduction in Wnt/beta-catenin transactivation incubated for 24 hrs by Wnt-responsive FOP-Flash luciferase reporter assay | Homo sapiens | 13 | ALA4680104 | cell-based format | Scientific Literature | |
2. | ALA4681811 | Binding | Inhibition of protein interaction between C-terminal 6x-histidine tagged full-length beta-catenin (1 to 781 residues) (unknown origin)/N-terminal biotinylated human BCL9 ( 350 to 375 residues) incubated for 1 hr by Alpha-screen competitive inhibition assay | Homo sapiens | 32 | ALA4680104 | protein complex format | Scientific Literature | |
3. | ALA4681818 | Functional | Cytotoxicity in human SW480 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 32 | ALA4680104 | cell-based format | Scientific Literature | |
4. | ALA4681819 | Functional | Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 19 | ALA4680104 | cell-based format | Scientific Literature | |
5. | ALA4681820 | Functional | Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 14 | ALA4680104 | cell-based format | Scientific Literature | |
6. | ALA4681821 | Functional | Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay | Homo sapiens | 16 | ALA4680104 | cell-based format | Scientific Literature | |
7. | ALA4681823 | Binding | Inhibition of protein interaction between beta-catenin (unknown origin)/BCL9 in human SW480 cells transfected with beta-catenin assessed as reduction in Wnt/beta-catenin transactivation incubated for 24 hrs by Wnt-responsive TOP-Flash luciferase reporter assay | Homo sapiens | 17 | ALA4680104 | cell-based format | Scientific Literature | |
8. | ALA4681824 | ADME | Cytotoxic activity in human SW480 cells at 50 to 100 uM incubated for 4 hrs by LDH release assay | Homo sapiens | 18 | ALA4680104 | cell-based format | Scientific Literature | |
9. | ALA4681826 | Binding | Inhibition of protein interaction between beta-catenin (unknown origin)/BCL9 in HEK293 cells transfected with beta-catenin assessed as reduction in Wnt/beta-catenin transactivation incubated for 24 hrs by Wnt-responsive FOP-Flash luciferase reporter assay | Homo sapiens | 13 | ALA4680104 | cell-based format | Scientific Literature |