# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4686182 | Binding | Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA | Homo sapiens | 24 | ALA4680229 | single protein format | Scientific Literature | |
2. | ALA4686183 | Binding | Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA | Homo sapiens | 15 | ALA4680229 | single protein format | Scientific Literature | |
3. | ALA4686184 | Binding | Selectivity index, ratio of IC50 for inhibition of human COX1 to IC50 for inhibition of human COX2 | Homo sapiens | 8 | ALA4680229 | assay format | Scientific Literature | |
4. | ALA4686185 | ADME | Cytotoxicity against rat C6 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Rattus norvegicus | 23 | ALA4680229 | cell-based format | Scientific Literature | |
5. | ALA4686186 | ADME | Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Mus musculus | 23 | ALA4680229 | cell-based format | Scientific Literature | |
6. | ALA4686187 | Functional | Inhibition of LPS-induced NO production in rat C6 cells incubated for 24 hrs by Griess reagent based assay | Rattus norvegicus | 15 | ALA4680229 | cell-based format | Scientific Literature | |
7. | ALA4686188 | Functional | Inhibition of LPS-induced NO production in mouse BV-2 cells incubated for 24 hrs by Griess reagent based assay | Mus musculus | 15 | ALA4680229 | cell-based format | Scientific Literature | |
8. | ALA4819643 | Functional | Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature | |
9. | ALA4819644 | Functional | Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature | |
10. | ALA4819645 | Functional | Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature | |
11. | ALA4819646 | Functional | Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature | |
12. | ALA4819647 | Functional | Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature | |
13. | ALA4819648 | Functional | Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature | |
14. | ALA4819649 | Functional | Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature | |
15. | ALA4819650 | Functional | Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 17 | ALA4818998 | cell-based format | Scientific Literature |