# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4730107 | ADME | Antiproliferative activity against human H1650 cells assessed as reduction in cell viability after 72 hrs by cell titer glow assay | Homo sapiens | 38 | ALA4725396 | cell-based format | Scientific Literature | |
2. | ALA4730108 | Binding | Inhibition of recombinant His-tagged human ATG7 incubated for 105 mins in presence of GST-tagged ATG3 and Flag-tagged Gabarap and measured after 2 hrs by FRET assay relative to control | Homo sapiens | 38 | ALA4725396 | single protein format | Scientific Literature | |
3. | ALA4730109 | Binding | Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 4 hrs by Western blot analysis | Homo sapiens | 30 | ALA4725396 | cell-based format | Scientific Literature | |
4. | ALA4730110 | Functional | Induction of autophagy in human H4 cells assessed as decrease in LC3B spot area by immunofluorescence assay | Homo sapiens | 38 | ALA4725396 | cell-based format | Scientific Literature | |
5. | ALA4730116 | Binding | Inhibition of ATG7 in human 293HEK cells assessed as inhibition of ATG7:ATG8 thioester formation after 8 hrs by Western blot analysis | Homo sapiens | 30 | ALA4725396 | cell-based format | Scientific Literature |