# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4704260 | Binding | Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity | Homo sapiens | 42 | ALA4699588 | single protein format | Scientific Literature | |
2. | ALA4704261 | Binding | Inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activity | Homo sapiens | 42 | ALA4699588 | single protein format | Scientific Literature | |
3. | ALA4704262 | Binding | Selectivity index, ratio of IC50 for inhibition of human constitutive 20S proteasome beta 5 chymotrypsin-like activity to IC50 for inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity | Homo sapiens | 42 | ALA4699588 | assay format | Scientific Literature | |
4. | ALA4704263 | Binding | Inhibition of human 20S immunoproteasome beta 1 at 33.3 uM relative to control | Homo sapiens | 6 | ALA4699588 | single protein format | Scientific Literature | |
5. | ALA4704264 | Binding | Inhibition of human 20S constitutive proteasome beta 1 at 33.3 uM relative to control | Homo sapiens | 6 | ALA4699588 | single protein format | Scientific Literature | |
6. | ALA4704265 | Binding | Inhibition of human 20S constitutive proteasome beta 2 at 33.3 uM relative to control | Homo sapiens | 6 | ALA4699588 | single protein format | Scientific Literature | |
7. | ALA4704266 | Binding | Inhibition of human 20S immunoproteasome beta 2 at 33.3 uM relative to control | Homo sapiens | 6 | ALA4699588 | single protein format | Scientific Literature | |
8. | ALA4704267 | Binding | Inhibition of alpha-chymotrypsin (unknown origin) at 11.1 to 1000 uM | Homo sapiens | 6 | ALA4699588 | assay format | Scientific Literature | |
9. | ALA4704268 | Binding | Inhibition of cathepsin L (unknown origin) at 11.1 to 1000 uM | Homo sapiens | 6 | ALA4699588 | single protein format | Scientific Literature | |
10. | ALA4704269 | Binding | Inhibition of trypsin (unknown origin) at 11.1 to 1000 uM | Homo sapiens | 6 | ALA4699588 | protein format | Scientific Literature | |
11. | ALA4704270 | Binding | Noncompetitive inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA4699588 | single protein format | Scientific Literature | |
12. | ALA4704271 | Binding | Inhibition of human 20S immunoproteasome beta 5 chymotrypsin-like activity in human KARPAS-1106P cells incubated for 2 hrs by proteasome-Glo assay | Homo sapiens | 6 | ALA4699588 | cell-based format | Scientific Literature | |
13. | ALA4704272 | Binding | Inhibition of human 20S constitutive proteasome beta 5 chymotrypsin-like activity in human HeLa cells incubated for 2 hrs by proteasome-Glo assay | Homo sapiens | 6 | ALA4699588 | cell-based format | Scientific Literature | |
14. | ALA4704273 | Functional | Inhibition of anti-CD3 antibody-stimulated T cell proliferation in human PBMCs | Homo sapiens | 6 | ALA4699588 | tissue-based format | Scientific Literature |