# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4735572 | Binding | Inhibition of recombinant human MMP2 (110 to 452 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in yeast expression system as substrate incubated for 15 mins followed by substrate addition and measured after 2 to 4 hrs by fluorescence based assay | Homo sapiens | 20 | ALA4732123 | assay format | Scientific Literature | |
2. | ALA4735573 | Binding | Inhibition of recombinant human MMP8 (99 to 269 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system as substrate incubated for 15 mins followed by substrate addition and measured after 2 to 4 hrs by fluorescence based assay | Homo sapiens | 20 | ALA4732123 | assay format | Scientific Literature | |
3. | ALA4735574 | Binding | Inhibition of recombinant human MMP9 (107 to 449 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system as substrate incubated for 15 mins followed by substrate addition and measured after 2 to 4 hrs by fluorescence based assay | Homo sapiens | 20 | ALA4732123 | assay format | Scientific Literature | |
4. | ALA4735575 | Binding | Inhibition of recombinant human MMP13 (104 to 274 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system as substrate incubated for 15 mins followed by substrate addition and measured after 2 to 4 hrs by fluorescence based assay | Homo sapiens | 19 | ALA4732123 | assay format | Scientific Literature | |
5. | ALA4735580 | ADME | Cytotoxicity against mouse SN-56 cells assessed as reduction in cell viability upto 100 uM incubated for 24 hrs by MTT assay | Mus musculus | 20 | ALA4732123 | cell-based format | Scientific Literature |