| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4701822 | Binding | Displacement of [3H]-Ro15-1788 from human GABAA alpha5beta3gamma2 by scintillation proximity assay | Homo sapiens | 35 | ALA4699487 | protein complex format | Scientific Literature | |
| 2. | ALA4701823 | Binding | Negative allosteric modulation of recombinant human GABA-A alpha5 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control | Homo sapiens | 30 | ALA4699487 | cell-based format | Scientific Literature | |
| 3. | ALA4701824 | ADME | Negative allosteric modulation of recombinant human GABA-A alpha1 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control | Homo sapiens | 22 | ALA4699487 | cell-based format | Scientific Literature | |
| 4. | ALA4701826 | ADME | Negative allosteric modulation of recombinant human GABA-A alpha3 expressed in HEK293 cells assessed as reduction in GABA-induced current at 1 uM relative to control | Homo sapiens | 21 | ALA4699487 | cell-based format | Scientific Literature | |
| 5. | ALA4701827 | ADME | Half life in rat liver microsomes | Rattus norvegicus | 31 | ALA4699487 | microsome format | Scientific Literature | |
| 6. | ALA4701828 | ADME | Half life in human liver microsomes | Homo sapiens | 31 | ALA4699487 | microsome format | Scientific Literature |
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